Browsing William Harvey Research Institute by Title

Vagal determinants of exercise capacity

Machhada, A; Trapp, S; Marina, N; Stephens, RCM; Whittle, J; Lythgoe, MF; Kasparov, S; Ackland, GL; Gourine, AV (2017-05-18)

Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the alpha 7nAChR subunit

Caravaca, AS; Gallina, AL; Tarnawski, L; Shavva, VS; Colas, RA; Dalli, J; Malin, SG; Hult, H; Arnardottir, H; Olofsson, PS (2022)

Validating benefit of biomarker-directed therapy for acute kidney injury: can you have your cake and eat it?

Prowle, JR; Schetz, M (2017-04)

Validation of 2D Flow MRI for Helical and Vortical Flows

Petersen, S; Aung, N

Validation of Cardiovascular Magnetic Resonance-Derived Equation for Predicted Left Ventricular Mass Using the UK Biobank Imaging Cohort: Tool for Donor-Recipient Size Matching.

Fung, K; Cheshire, C; Cooper, JA; Catarino, P; Piechnik, SK; Neubauer, S; Bhagra, S; Pettit, S; Petersen, SE (2019-12)

BACKGROUND: Current guidance from International Society for Heart and Lung Transplantation recommends using body weight for donor-recipient size matching for heart transplantation. However, recent studies have shown that ...

Validation of Clinically Relevant Variant Detection from Whole Genome Sequencing for NHS England's Genomic Medicine Service

Kasperaviciute, D; Smith, KR; Ibanez, K; Pasko, D; Bleda, M; Walker, S; Polychronopoulos, D; Martin, AR; Kayikci, M; Lopez, J (2020-12)

Validation of the all-comers design: Results of the TARGET-AC substudy.

G Toth, G; Lansky, A; Baumbach, A; Kelbæk, H; van Royen, N; Holmvang, L; Janssens, L; Brugaletta, S; Barbato, E; Maillard, L (2020-03)

BACKGROUND: Results of clinical trials are often criticized by low inclusion rate and potential sampling bias in patient recruitment. The aim of this validation registry is to evaluate how far an all-comers design in the ...

Validation of the CREST score for predicting circulatory-aetiology death in out-of-hospital cardiac arrest without STEMI

Jones, TN; Kelham, M; Rathod, KS; Knight, CJ; Proudfoot, A; Jain, AK; Wragg, A; Ozkor, M; Rees, P; Guttmann, O (2021)

Validation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery

Ahmed, WUR; Bhatia, S; McLean, KA; Khaw, R; Baker, D; Kamarajah, SK; Bell, S; Nepogodiev, D; Harrison, EM; Glasbey, JC (2022)

Validity of a two-component imaging-derived disease activity score for improved assessment of synovitis in early rheumatoid arthritis

Hensor, EMA; McKeigue, P; Buch, MH; Barrett, JH; Nam, JL; Freeston, J; Colombo, M; Spiliopoulou, A; Agakov, F; Kelly, S (Oxford University Press on behalf of the British Society for Rheumatology., 2018-04-25)

Objectives. Imaging of joint inflammation provides a standard against which to derive an updated DAS for RA. Our objectives were to develop and validate a DAS based on reweighting the DAS28 components to maximize ...

Validity of inducible ischaemia as a surrogate for adverse outcomes in stable coronary artery disease

Timmis, A; Raharja, A; Archbold, RA; Mathur, A (2018)

The value of whole exome sequencing for genetic diagnosis in a patient with Bloom syndrome

Cottrell, E; Ladha, T; Borysewicz-Sanczyk, H; Sawicka, B; Savage, MO; Bossowski, AT; Storr, HL (2020-09-29)

Variability in content and dissolution profiles of MDMA tablets collected in the UK between 2001 and 2018-A potential risk to users?

Couchman, L; Frinculescu, A; Sobreira, C; Shine, T; Ramsey, J; Hecht, M; Kipper, K; Holt, D; Johnston, A (2019-08)

Variability in Serum Sodium Concentration and Prognostic Significance in Severe Traumatic Brain Injury: A Multicenter Observational Study

Harrois, A; Anstey, JR; van der Jagt, M; Taccone, FS; Udy, AA; Citerio, G; Duranteau, J; Ichai, C; Badenes, R; Prowle, JR (2020-10-02)

Variable selection and risk prediction using a penalised modelling framework for high-dimensional data in a nested matched case-control design

Timmons, J; RSS International Conference 2022 (https://rss.org.uk/training-events/conference2022/, 2022-09-12)

In a matched case-control (MCC) study, each subject with the outcome of interest (case) is matched with m subjects without the outcome (control) from the same cohort (often called a 1:m nested MCC). This design is efficient ...

Variables associated with successful outcome after anterior cruciate ligament reconstruction in recreational athletes: A prospective cohort study

Neal, BS; Miller, SC; Goodall, A; Phillips, J; Small, C; Lack, SD (2022)

Variants in Methyl-CpG-binding protein 2 (MECP2) are associated with X-Linked Central Precocious Puberty

E, RJ; Pinheiro-Machado, CA; Tinano, F; Guasti, L; Ribeiro, ML; Ryan, F; Shears, D; Paganoni, A; Korbonits, M; Jorge, A

Variants in the Mannose-binding Lectin Gene MBL2 do not Associate With Sepsis Susceptibility or Survival in a Large European Cohort.

Mills, TC; Chapman, S; Hutton, P; Gordon, AC; Bion, J; Chiche, J-D; Holloway, PAH; Stüber, F; Garrard, CS; Hinds, CJ (2015-09-01)

BACKGROUND: Sepsis is an increasingly common condition, which continues to be associated with unacceptably high mortality. A large number of association studies have investigated susceptibility to, or mortality from, sepsis ...

Variation in left ventricular cardiac magnetic resonance normal reference ranges: systematic review and meta-analysis

Petersen, S; Aung, N; Munroe, P; Raisi-Estabragh, Z; Khanji, M; Cooper, J (Oxford University Press (OUP), 2020-05-27)

Variation in lung function and alterations in cardiac structure and function-Analysis of the UK Biobank cardiovascular magnetic resonance imaging substudy

Thomson, RJ; Aung, N; Sanghvi, MM; Paiva, JM; Lee, AM; Zemrak, F; Fung, K; Pfeffer, PE; Mackay, AJ; McKeever, TM (2018-03-20)