Browsing William Harvey Research Institute by Title
Now showing items 4374-4393 of 4755
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T cell metabolism. The protein LEM promotes CD8⁺ T cell immunity through effects on mitochondrial respiration.
(2015-04-16)Protective CD8(+) T cell-mediated immunity requires a massive expansion in cell number and the development of long-lived memory cells. Using forward genetics in mice, we identified an orphan protein named lymphocyte expansion ... -
T-wave morphology abnormalities in the STREAM stage 1 trial.
(2024-04)BACKGROUND: Shorter regimens for drug-resistant tuberculosis (DR-TB) have non-inferior efficacy compared with longer regimens, but QT prolongation is a concern. T-wave morphology abnormalities may be a predictor of QT ... -
T-wave Peak-to-End Changes Quantified by Time-Warping Predicts Ventricular Fibrillation in a Porcine Myocardial Infarction Model.
(2024-05-22)BACKGROUND: The T-peak-to-T-end ( Tpe) interval has shown potential in predicting ventricular arrhythmic risk. It is an appealing index to be measured during ischemia since it is less influenced by ST-segment changes than ... -
Tailoring the treatment of inflammatory rheumatic diseases by a better stratification and characterization of the clinical patient heterogeneity. Findings from a systematic literature review and experts' consensus.
(2024)Inflammatory rheumatic diseases are different pathologic conditions associated with a deregulated immune response, codified along a spectrum of disorders, with autoinflammatory and autoimmune diseases as two-end phenotypes ... -
Talking to multi-morbid patients about critical illness: an evolving conversation.
(2021-06-11)Conversations around critical illness outcomes and benefits from intensive care unit (ICU) treatment have begun to shift away from binary discussions on living versus dying. Increasingly, the reality of survival with ... -
Tall stature and gigantism in adult patients with acromegaly.
(2024-03-02)OBJECTIVES: Increased height in patients with acromegaly could be a manifestation of growth hormone (GH) excess before epiphysis closure. The aim of this study was to evaluate the relationship between the height of adult ... -
TAMOR a Thermal-Aware MultihOp Routing protocol for Ultrasonic Intra Body Area Networks
(2017-05-13)The rise in population aging witnesses the widespread attention towards the healthcare also by means of efficient and non invasive healthcare monitoring platforms. Intra Body Area Networks (I-BANs) are envisaged as the ... -
Targeted therapy with a localised abluminal groove, low-dose sirolimus-eluting, biodegradable polymer coronary stent (TARGET All Comers): a multicentre, open-label, randomised non-inferiority trial.
(Elsevier, 2018-09-29)Summary Background The FIREHAWK is a drug-eluting stent with a fully biodegradable sirolimus-containing polymer coating localised to recessed abluminal grooves on the stent surface. We investigated clinical outcomes with ...