Browsing William Harvey Research Institute by Title

Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial

Jhanji, S; Vivian-Smith, A; Lucena-Amaro, S; Watson, D; Hinds, CJ; Pearse, RM (2010)

Harmonisation of large-scale, heterogeneous individual participant adverse event data from randomised trials of statin therapy.

Cholesterol Treatment Trialists' Collaboration (SAGE Publications, 2022-07-09)

BACKGROUND: Meta-analyses of individual-level data from randomised trials are often required to detect clinically worthwhile effects. The Cholesterol Treatment Trialists' Collaboration, which includes data from numerous ...

Harmonizing and improving European education in prescribing: An overview of digital educational resources used in clinical pharmacology and therapeutics.

Bakkum, MJ; Tichelaar, J; Papaioannidou, P; Likic, R; Sanz Alvarez, EJ; Christiaens, T; Costa, JN; Mačiulaitis, R; Dima, L; Coleman, J (2021-03)

AIM: Improvement and harmonization of European clinical pharmacology and therapeutics (CPT) education is urgently required. Because digital educational resources can be easily shared, adapted to local situations and re-used ...

Harnessing gene-gene interactions via an RNA-Sequencing network analysis framework improves precision medicine prediction in rheumatoid arthritis

Sciacca, E; Surace, A; Alaimo, S; Pulvirenti, A; Rivellese, F; Goldmann, K; Ferro, A; Latora, V; Pitzalis, C; Lewis, M (2021)

Harnessing the Therapeutic Potential of Th17 Cells

Bystrom, J; Taher, TE; Muhyaddin, MS; Clanchy, FI; Mangat, P; Jawad, AS; Williams, RO; Mageed, RA (2015)

Have biomarkers failed in acute kidney injury? We are not sure

Prowle, JR; Rosner, MH (2017-06)

Have the Findings from Clinical Risk Prediction and Trials Any Key Messages for Safety Pharmacology?

Lane, JD; Tinker, A (2017)

Anti-arrhythmic drugs are a mainstay in the management of symptoms related to arrhythmias, and are adjuncts in prevention and treatment of life-threatening ventricular arrhythmias. However, they also have the potential for ...

Head and neck cancer surgery during the COVID-19 pandemic: An international, multicenter, observational cohort study.

COVIDSurg Collaborative (Wiley Periodicals LLC on behalf of American Cancer Society, 2021-07-15)

BACKGROUND: The aims of this study were to provide data on the safety of head and neck cancer surgery currently being undertaken during the coronavirus disease 2019 (COVID-19) pandemic. METHODS: This international, ...

Head-to-Head Comparison of Near-Infrared Spectroscopy-Intravascular Ultrasound and Coronary Computed Tomography Angiography in Assessing Atheroma Characteristics.

Ramasamy, A; Pugliese, F; Tanboga, IH; Kitslaar, P; Dijkstra, J; Mathur, A; Torii, R; Moon, JC; Baumbach, A; Bourantas, CV (Elsevier, 2024-09-11)

Health data science course for clinicians: Time to bridge the skills gap?

Naderi, H; Yang, YH; Munroe, PB; Petersen, SE; Westwood, M; Aung, N (SAGE Publications, 2024-10-11)

Background: Data science skills are highly relevant for clinicians working in an era of big data in healthcare. However, these skills are not routinely taught, representing a growing unmet educational need. This education ...

Health Economics, Economic Evaluation and Artificial Intelligence Technology

Petersen, SE; Uchegbu, I; Abdulkareem, M; Rua, T; Kartha, MR; Rodriguez-Guadarrama, Y

Health economics is the study of allocating scarce goods within a healthcare market. Due to constrained budgets, clinical effectiveness is not enough to inform healthcare planning and provision. Economic evaluation enables ...

Health position paper and redox perspectives on reactive oxygen species as signals and targets of cardioprotection.

Heusch, G; Andreadou, I; Bell, R; Bertero, E; Botker, H-E; Davidson, SM; Downey, J; Eaton, P; Ferdinandy, P; Gersh, BJ (2023-11)

The present review summarizes the beneficial and detrimental roles of reactive oxygen species in myocardial ischemia/reperfusion injury and cardioprotection. In the first part, the continued need for cardioprotection beyond ...

Health Resource Utilisation and Disparities: an Ecological Study of Admission Patterns Across Ethnicity in England Between 2017 and 2020

Toal, CM; Fowler, AJ; Pearse, RM; Puthucheary, Z; Prowle, JR; Wan, YI (2022)

Health-related quality of life and healthcare costs of symptoms and cardiovascular disease events in patients with atrial fibrillation: a longitudinal analysis of 27 countries from the EURObservational Research Programme on Atrial Fibrillation general long-term registry.

Walli-Attaei, M; Little, M; Luengo-Fernandez, R; Gray, A; Torbica, A; Maggioni, AP; Bairami, F; Huculeci, R; Aboyans, V; Timmis, AD (2024-06-03)

AIMS: We examine the effects of symptoms and cardiovascular disease (CVD) events on health-related quality of life (HRQOL) and healthcare costs in a European population with atrial fibrillation (AF). METHODS AND RESULTS: ...

Health-related quality of life in cardiac sarcoidosis: a systematic review.

Quijano-Campos, JC; Sekhri, N; Thillai, M; Sanders, J (2023-03)

People living with cardiac sarcoidosis (CS) are likely to have worse clinical outcomes and greater impairment on health-related quality of life (HRQoL) than other sarcoidosis manifestations. CS can result in a constellation ...

Healthcare utilisation of 282,080 individuals with long COVID over two years: a multiple matched control, longitudinal cohort analysis.

Mu, Y; Dashtban, A; Mizani, MA; Tomlinson, C; Mohamed, M; Ashworth, M; Mamas, M; Priedon, R; Petersen, S; Kontopantelis, E (SAGE Publications, 2024-11-27)

OBJECTIVES: To investigate healthcare utilisation and cost in individuals with long COVID (LC) at population level. DESIGN: Case-control cohort analysis with multiple age-, sex-, ethnicity-, deprivation-, region- and ...

Healthcare Workers Bioresource: Study outline and baseline characteristics of a prospective healthcare worker cohort to study immune protection and pathogenesis in COVID-19

Augusto, JB; Menacho, K; Andiapen, M; Bowles, R; Burton, M; Welch, S; Bhuva, AN; Seraphim, A; Pade, C; Joy, G (2020-10-12)

Healthcare Workers Bioresource: Study outline and baseline characteristics of a prospective healthcare worker cohort to study immune protection and pathogenesis in COVID-19

Augusto, JB; Menacho, K; Andiapen, M; Bowles, R; Burton, M; Welch, S; Bhuva, AN; Seraphim, A; Pade, C; Joy, G (2020-10-12)

HEALTHIER CMR PHENOTYPES ARE LINKED TO FAVOURABLE BRAIN MRI STRUCTURE AND FUNCTION METRICS IN THE UK BIOBANK

McCracken, C; Raisi-Estabragh, Z; Raman, B; Dennis, A; Nichols, TE; Husain, M; Petersen, SE; Neubauer, S (2021)

Heart Failure Following Anti-Inflammatory Medications in Patients With Type 2 Diabetes Mellitus

Holt, A; Strange, JE; Nouhravesh, N; Nielsen, SK; Malik, ME; Schjerning, A-M; Kober, L; Torp-Pedersen, C; Gislason, GH; McGettigan, P (Elsevier, 2023-04-10)