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Genetic regulation of mouse glycosylphosphatidylinositol-phospholipase D

Flores-Borja, F; Kieszkievicz, J; Church, V; Francis-West, PH; Schofield, J; Rademacher, TW; Lund, T (Elsevier, 2004-04-23)

Glycosylphosphatidylinositol phospholipase D (GPI-PLD) has been proposed to be responsible for cleaving membrane-associated glycosylphosphatidyl inositol (GPI) molecules to generate inositol phosphoglycan (IPGs), which ...

Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis

Flores-Borja, F; Jury, EC; Mauri, C; Ehrenstein, MR (National Academy of Sciences, 2008-12-09)

The ultimate goal for the treatment of autoimmunity is to restore immunological tolerance. Regulatory T cells (Treg) play a central role in immune tolerance, and Treg functional abnormalities have been identified in different ...

Restoring the balance: Harnessing regulatory T cells for therapy in rheumatoid arthritis

Flores-Borja, F; Mauri, C; Ehrenstein, MR (2008-04)

Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus

Jury, EC; Kabouridis, PS; Flores-Borja, F; Mageed, RA; Isenberg, DA (2004-04)

Altered lipid raft-associated proximal signaling and translocation of CD45 tyrosine phosphatase in B lymphocytes from patients with systemic lupus erythematosus

Flores-Borja, F; Kabouridis, PS; Jury, EC; Isenberg, DA; Mageed, RA (2007-01)

Lipid rafts in T cell signalling and disease

Jury, EC; Flores-Borja, F; Kabouridis, PS (2007-10)

Decreased Lyn expression and translocation to lipid raft signaling domains in B lymphocytes from patients with systemic lupus erythematosus

Flores-Borja, F; Kabouridis, PS; Jury, EC; Isenberg, DA; Mageed, RA (2005-12)