Now showing items 1-7 of 7
Genetic regulation of mouse glycosylphosphatidylinositol-phospholipase D
Glycosylphosphatidylinositol phospholipase D (GPI-PLD) has been proposed to be responsible for cleaving membrane-associated glycosylphosphatidyl inositol (GPI) molecules to generate inositol phosphoglycan (IPGs), which ...
Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis
(National Academy of Sciences, 2008-12-09)
The ultimate goal for the treatment of autoimmunity is to restore immunological tolerance. Regulatory T cells (Treg) play a central role in immune tolerance, and Treg functional abnormalities have been identified in different ...