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Microbial Translocation Does Not Drive Immune Activation in Ugandan Children Infected With HIV.
(Oxford University Press, 2019-01-01)
Objective: Immune activation is associated with morbidity and mortality during human immunodeficiency virus (HIV) infection, despite receipt of antiretroviral therapy (ART). We investigated whether microbial translocation ...
Reduced bacterial skin infections in HIV-infected African children randomized to long-term cotrimoxazole prophylaxis
(Wolters Kluwer Health, Inc, 2016-11-28)
Objective:
To evaluate whether cotrimoxazole prophylaxis prevents common skin conditions in HIV-infected children.
Design:
Open-label randomized controlled trial of continuing versus stopping daily cotrimoxazole ...
Baseline Inflammatory Biomarkers Identify Subgroups of HIV-Infected African Children With Differing Responses to Antiretroviral Therapy
(Oxford University Press, 2016-05-18)
Background. Identifying determinants of morbidity and mortality may help target future interventions for human immunodeficiency virus (HIV)–infected children.
Methods. CD4+ T-cell count, HIV viral load, and levels of ...
Head circumferences of children born to HIV-infected and HIV-uninfected mothers in Zimbabwe during the preantiretroviral therapy era
(Lippincott, Williams & Wilkins, 2016-09-24)
Objectives: To describe the head growth of children according to maternal and child
HIV infection status.
Design: Longitudinal analysis of head circumference data from 13 647 children
followed from birth in the ZVITAMBO ...
Current Understanding of Innate Immune Cell Dysfunction in Childhood Undernutrition.
(2019)
Undernutrition affects millions of children in low- and middle-income countries (LMIC) and underlies almost half of all deaths among children under 5 years old. The growth deficits that characterize childhood undernutrition ...
Postdischarge interventions for children hospitalized with severe acute malnutrition: a systematic review and meta-analysis.
(2021-01-30)
BACKGROUND: Children hospitalized with severe acute malnutrition (SAM) have poor long-term outcomes following discharge, with high rates of mortality, morbidity, and impaired neurodevelopment. There is currently minimal ...