Browsing Blizard Institute by Title
Now showing items 2152-2171 of 5325
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GPR84 in physiology-Many functions in many tissues.
(2023-08-02)Members of the GPCR superfamily have a wide variety of physiological roles and are therefore valuable targets for developing effective medicines. However, within this superfamily are receptors that are less well characterized ... -
Grading evidence from test accuracy studies: what makes it challenging compared with the grading of effectiveness studies?
(2017-06)Guideline panels need to process a sizeable amount of information to issue a decision on whether to recommend a health technology or not. Grading of Recommendations Assessment, Development, and Evaluation (GRADE) is being ... -
Group B or Not Group B? An Association Between ABO, Early Mortality, and Organ Dysfunction in Major Trauma Patients with Shock.
(2023-12-07)BACKGROUND: ABO group alters coagulation profiles in the general population and may influence outcomes after trauma. The relationship between trauma-induced coagulopathy, severe injury with haemorrhagic shock, and survival ... -
Group clinics for young adults living with diabetes in an ethnically diverse, socioeconomically deprived population: mixed-methods evaluation
(2022-01-01)Background: Our research was based on the expressed need to evaluate the potential for group clinics to enhance care within the NHS for people with long-term conditions. Objectives: We aimed to explore the scope, feasibility, ... -
Group-based cognitive stimulation therapy for dementia: a qualitative study on experiences of group interactions
Objectives: Cognitive Stimulation Therapy (CST) is an evidence-based group intervention shown to improve cognition and quality of life in dementia and is widely implemented across the NHS. However, no attempt has been made ... -
Growth and Viability of Cutaneous Squamous Cell Carcinoma Cell Lines Display Different Sensitivities to Isoform-Specific Phosphoinositide 3-Kinase Inhibitors.
(MDPI, 2021-03-30)Cutaneous squamous cell carcinomas (cSCCs) account for about 20% of keratinocyte carcinomas, the most common cancer in the UK. Therapeutic options for cSCC patients who develop metastasis are limited and a better understanding ... -
Guidance for design and endpoints of clinical trials in chronic hepatitis B - Report from the 2019 EASL-AASLD HBV Treatment Endpoints Conference.
(2019-11-12)Representatives from academia, industry, regulatory agencies, and patient groups convened in March 2019 with the primary goal of developing agreement on chronic hepatitis B virus (HBV) treatment endpoints to guide clinical ... -
Guidelines for reporting embedded recruitment trials
(2016-01-14)