Browsing Blizard Institute by Title
Now showing items 1785-1804 of 5326
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Evidence for long-term sensitization of the bowel in patients with post-infectious-IBS.
(2017-10-19)Post-infectious irritable bowel syndrome (PI-IBS) is a common gastrointestinal disorder characterized by persistent abdominal pain despite recovery from acute gastroenteritis. The underlying mechanisms are unclear, although ... -
Evidence for tetrodotoxin-resistant spontaneous myogenic contractions of mouse isolated stomach that are dependent on acetylcholine.
(Wiley, 2021-09-14)BACKGROUND AND PURPOSE: Gastric pacemaker cells (interstitial cells of Cajal; ICC) are believed to initiate myogenic (non-neuronal) contractions. These become damaged in gastroparesis, associated with dysrhythmic electrical ... -
Evidence for the presence of air pollution nanoparticles in placental tissue cells
Inhaled particulate matter (PM) from combustion- and frictionsourced air pollution adversely affects organs distant from the lung. A putative mechanism for the remote effect of inhaled PM is that ultrafine, nano-sized ... -
Evidence of Clostridium perfringens epsilon toxin associated with multiple sclerosis.
(Sage Publications, 2018-04-21)BACKGROUND: It was recently reported that, using Western blotting, some multiple sclerosis (MS) patients in the United States had antibodies against epsilon toxin (Etx) from Clostridium perfringens, suggesting that the ... -
Evidence that 5-hydroxytryptamine3 receptors mediate cytotoxic drug and radiation-evoked emesis
(Macmillan Press, 1987)The involvement of 5-hydroxytryptamine (5-HT) 5-HT3 receptors in the mechanisms of severe emesis evoked by cytotoxic drugs or by total body irradiation have been studied in ferrets. Anti-emetic compounds tested were ... -
Evidence That Links Cyclo-oxygenase-2 Inhibition With Increased Asymmetric Dimethylarginine: Novel Explanation of Cardiovascular Side Effects Associated With Anti-inflammatory Drugs
(American Heart Association, 2018-03-27)Inhibition of cyclo-oxygenase (COX)-2 by nonsteroidal anti-inflammatory drugs (NSAIDs), including COX-2 selective inhibitors such as celecoxib and rofecoxib, is associated with cardiovascular side effects. It was previously ... -
Evidence-Based Guideline on Laparoscopy in Pregnancy: Commissioned by the British Society for Gynaecological Endoscopy (BSGE) Endorsed by the Royal College of Obstetricians & Gynaecologists (RCOG).
(2019-03)Laparoscopy is widely utilised to diagnose and treat acute and chronic, gynaecological and general surgical conditions. It has only been in recent years that laparoscopy has become an acceptable surgical alternative to ... -
The 'evil twin syndrome' in chronic pelvic pain: a systematic review of prevalence studies of bladder pain syndrome and endometriosis.
(Elsevier, 2013-03-04)BACKGROUND: Chronic pelvic pain (CPP), a common gynaecological presentation, may be due to bladder pain syndrome (BPS) or the co-existence of BPS and endometriosis, known as the 'evil twins syndrome'. OBJECTIVES: To estimate ... -
Ex vivo study of human visceral nociceptors
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Excess Gestational Weight Gain in Pregnancy and the Role of Lifestyle Intervention.
(2016-03)With increasingly adverse lifestyles, young women in many countries have rapid weight gain and rising obesity. In keeping with this, most pregnant women exceed recommended gestational weight gain (GWG) and then retain ...