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Discrepancies in the Tumor Microenvironment of Spontaneous and Orthotopic Murine Models of Pancreatic Cancer Uncover a New Immunostimulatory Phenotype for B Cells.
(2019)
B cells are salient features of pancreatic ductal adenocarcinoma (PDAC) tumors, yet their role in this disease remains controversial. Murine studies have indicated a protumoral role for B cells, whereas clinical data show ...
Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer
(Elsevier, 2021-05)
In a multi-level ‘deconstruction’ of omental metastases, we previously identified a prognostic matrisome gene expression signature in high-grade serous ovarian cancer (HGSOC) and twelve other malignancies. Here, our aim ...
Modelling TGF beta R and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer
(Cell Press, 2021-05-29)