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Durable graft-versus-leukaemia effects without donor lymphocyte infusions - results of a phase II study of sequential T-replete allogeneic transplantation for high-risk acute myeloid leukaemia and myelodysplasia.

Davies, JK; Hassan, S; Sarker, S-J; Besley, C; Oakervee, H; Smith, M; Taussig, D; Gribben, JG; Cavenagh, JD (2018-02)

Allogeneic haematopoietic stem-cell transplantation remains the only curative treatment for relapsed/refractory acute myeloid leukaemia (AML) and high-risk myelodysplasia but has previously been limited to patients who ...

Final results of ProGem1, the first in-human phase I/II study of NUC-1031 in patients with solid malignancies.

Blagden, SP; Rizzuto, I; Stavraka, C; O'Shea, D; Suppiah, P; Patel, M; Sukumaran, A; Loyse, N; Bharwani, N; Rockall, A;... (2015-05-20)

A first in human Phase I/II study of NUC-1031 in patients with advanced gynecological cancers.

Blagden, SP; Rizzuto, I; Stavraka, C; O'Shea, D; Suppiah, P; Patel, M; Loyse, N; Sukumaran, A; Bharwani, N; Rockall, A;... (2015-05-20)

Late Effects: An Evaluation of Contrasting Physical and Psychological Experiences Between Child and Adult Hodgkin Survivors

Sarker, S-J; George, GE; Chowdhury, K; Levitt, G; Kingston, J; Lister, A; Gribben, JG; Korszun, A (2014-12-06)

Dysregulation of autophagy in human follicular lymphoma is independent of overexpression of BCL-2

McCarthy, A; Marzec, J; Clear, A; Petty, RD; Coutinho, R; Matthews, J; Wilson, A; Iqbal, S; Calaminici, M; Gribben, JG;... (2014-11-30)

Blocking Autophagy Prevents Bortezomib-Induced NF-kappa B Activation by Reducing I-kappa B alpha Degradation in Lymphoma Cells

Jia, L; Gopinathan, G; Sukumar, JT; Gribben, JG (2012-02-29)

Rituximab-induced HMGB1 release is associated with inhibition of STAT3 activity in human diffuse large B-cell lymphoma

Zhao, T; Ren, H; Wang, X; Liu, P; Yan, F; Jiang, W; Li, Y; Li, J; Gribben, JG; Jia, L;... (2015-09-29)

Empirical inference of circuitry and plasticity in a kinase signaling network

Wilkes, EH; Terfve, C; Gribben, JG; Saez-Rodriguez, J; Cutillas, PR (2015-06-23)

Metabolomic analysis of pegylated arginine deiminase treatment in patients with malignant pleural mesothelioma

Ghazaly, EA; Luong, P; Chmielewska-Kassassir, M; Wozniak, L; Bomalaski, JS; Gribben, JG; Szlosarek, PW (2014-05-20)

Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma

Okosun, J; Bödör, C; Wang, J; Araf, S; Yang, CY; Pan, C; Boller, S; Cittaro, D; Bozek, M; Iqbal, S;... (2014-02-01)

Follicular lymphoma is an incurable malignancy, with transformation to an aggressive subtype representing a critical event during disease progression. Here we performed whole-genome or whole-exome sequencing on 10 follicular ...