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Importance of serial CA125 measurements over an absolute cut-off value for the detection of asymptomatic ovarian cancer in high-risk patients.

Dilley, J; Manchanda, R; Johnson, M; Rosenthal, AN; Gessler, S; Menon, U (2016-05)

Defining the risk threshold for risk reducing salpingo-oophorectomy for ovarian cancer prevention in low risk postmenopausal women.

Manchanda, R; Legood, R; Pearce, L; Menon, U (2015-12)

OBJECTIVE: To define risk thresholds for cost-effectiveness of risk-reducing salpingo-oophorectomy (RRSO) for ovarian cancer (OC) prevention in low/intermediate risk postmenopausal women. METHODS: A decision-analytic model ...

Benchmarking of surgical complications in gynaecological oncology: prospective multicentre study.

Burnell, M; Iyer, R; Gentry-Maharaj, A; Nordin, A; Liston, R; Manchanda, R; Das, N; Gornall, R; Beardmore-Gray, A; Hillaby, K;... (2016-12)

OBJECTIVE: To explore the impact of risk-adjustment on surgical complication rates (CRs) for benchmarking gynaecological oncology centres. DESIGN: Prospective cohort study. SETTING: Ten UK accredited gynaecological oncology ...

Histological confirmation of breast cancer registration and self-reporting in England and Wales: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening.

Fourkala, EO; Gentry-Maharaj, A; Burnell, M; Ryan, A; Manchanda, R; Dawnay, A; Jacobs, I; Widschwendter, M; Menon, U (2012-06-05)

BACKGROUND: In research studies, accurate information of cancer diagnosis is crucial. In women with breast cancer (BC), we compare cancer registration (CR) in England/Wales and self-reporting with independent confirmation. ...

Setting the Threshold for Surgical Prevention in Women at Increased Risk of Ovarian Cancer.

Manchanda, R; Menon, U (2018-01)

The number of ovarian cancer cases is predicted to rise by 14% in Europe and 55% worldwide over the next 2 decades. The current absence of a screening program, rising drug/treatment costs, and only marginal improvements ...