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Lenalidomide Enhances Human Alloresponses By Increasing Proliferation of Effector Memory CD8 T Cells with Enhanced Polyfunctional Effector Capacity and a Unique Gene Expression Profile

Besley, CM; Kotsiou, E; Petty, R; Sangaralingum, A; Le Dieu, R; Gribben, JG; Davies, JK (2014-12-06)

Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma

Araf, S; Wang, J; Korfi, K; Pangault, C; Kotsiou, E; Rio-Machin, A; Rahim, T; Heward, J; Clear, A; Iqbal, S;... (2018-05)

TNFRSF14 aberrations in follicular lymphoma increase clinically significant allogeneic T-cell responses

Kotsiou, E; Okosun, J; Besley, C; Iqbal, S; Matthews, J; Fitzgibbon, J; Gribben, JG; Davies, JK (2016-07-07)

Durable graft-versus-leukaemia effects without donor lymphocyte infusions - results of a phase II study of sequential T-replete allogeneic transplantation for high-risk acute myeloid leukaemia and myelodysplasia.

Davies, JK; Hassan, S; Sarker, S-J; Besley, C; Oakervee, H; Smith, M; Taussig, D; Gribben, JG; Cavenagh, JD (2018-02)

Allogeneic haematopoietic stem-cell transplantation remains the only curative treatment for relapsed/refractory acute myeloid leukaemia (AML) and high-risk myelodysplasia but has previously been limited to patients who ...

Retinoic acid-responsive CD8 effector T-cells are selectively increased in IL-23-rich tissue in gastrointestinal GvHD.

Ball, JA; Clear, AJ; Aries, J; Charrot, S; Besley, C; Mee, M; Stagg, A; Lindsay, JO; Cavenagh, J; Calaminici, M;... (2020-09-09)

Gastrointestinal (GI) graft-versus-host disease (GvHD) is a major barrier in allogeneic hematopoietic stem-cell transplantation (AHST). The metabolite retinoic acid (RA) potentiates GI-GvHD in mice via alloreactive T-cells ...

Clinical outcome of coronavirus disease 2019 in haemato-oncology patients

Aries, JA; Davies, JK; Auer, RL; Hallam, SL; Montoto, S; Smith, M; Sevillano, B; Foggo, V; Wrench, B; Zegocki, K;... (2020)