Browsing Barts Cancer Institute by Author "Acar, A"
Now showing items 1-3 of 3
-
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer
Acar, A; Nichol, D; Fernandez-Mateos, J; Cresswell, GD; Barozzi, I; Hong, SP; Trahearn, N; Spiteri, I; Stubbs, M; Burke, R (Springer Science and Business Media LLC, 2020-12) -
Model-based tumor subclonal reconstruction
Caravagna, G; Heide, T; Williams, M; Zapata, L; Nichol, D; Chkhaidze, K; Cross, W; Cresswell, G; Werner, B; Acar, A (2019)The vast majority of cancer next-generation sequencing data consist of bulk samples composed of mixtures of cancer and normal cells. To study tumor evolution, subclonal reconstruction approaches based on machine learning ... -
Subclonal reconstruction of tumors by using machine learning and population genetics
Caravagna, G; Heide, T; Williams, MJ; Zapata, L; Nichol, D; Chkhaidze, K; Cross, W; Cresswell, GD; Werner, B; Acar, A (2020-09)