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dc.contributor.authorLeng, Yen_US
dc.contributor.authorCappuccio, FPen_US
dc.contributor.authorSurtees, PGen_US
dc.contributor.authorLuben, Ren_US
dc.contributor.authorBrayne, Cen_US
dc.contributor.authorKhaw, K-Ten_US
dc.date.accessioned2018-03-13T15:02:50Z
dc.date.available2016-06-17en_US
dc.date.issued2016-11en_US
dc.date.submitted2018-03-13T14:58:07.935Z
dc.identifier.other10.1016/j.numecd.2016.06.006
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0939475316300862?via%3Dihub
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/35043
dc.description.abstractBACKGROUND AND AIMS: Few studies have prospectively examined the relationship between daytime napping and risk of type 2 diabetes. We aimed to study the effects of daytime napping and the joint effects of napping and sleep duration in predicting type 2 diabetes risk in a middle- to older-aged British population. METHODS AND RESULTS: In 1998-2000, 13 465 individuals with no known diabetes participating in the European Prospective Investigation into Cancer-Norfolk study reported daytime napping habit and 24-h sleep duration. Incident type 2 diabetes cases were identified through multiple data sources until 31 July 2006. After adjustment for age and sex, daytime napping was associated with a 58% higher diabetes risk. Further adjustment for education, marital status, smoking, alcohol intake, physical activity, comorbidities and hypnotic drug use had little influence on the association, but additional adjustment for BMI and Waist Circumference attenuated the Odds ratio (OR) (95% CI) to 1.30 (1.01, 1.69). The adjusted ORs (95% CI) associated with short and long sleep duration were 1.46 (1.10, 1.90) and 1.64 (1.16, 2.32), respectively. When sleep duration and daytime napping were examined together, the risk of developing diabetes more than doubled for those who took day naps and had less than 6 h of sleep, compared to those who did not nap and had 6-8 h of sleep. CONCLUSION: Daytime napping was associated with an increased risk of type 2 diabetes, particularly when combined with short sleep duration. Further physiological studies are needed to confirm the interaction between different domains of sleep in relation to diabetes risk.en_US
dc.description.sponsorshipThe design and conduct of the EPIC-Norfolk study and collection and management of the data was supported by programme grants from the Medical Research Council UK (G9502233, G0300128) and Cancer Research UK (C865/A2883).en_US
dc.format.extent996 - 1003en_US
dc.languageengen_US
dc.language.isoenen_US
dc.relation.ispartofNutr Metab Cardiovasc Disen_US
dc.rightsCreative Commons Attribution License
dc.subjectCohorten_US
dc.subjectEpidemiologyen_US
dc.subjectProspectiveen_US
dc.subjectSleepen_US
dc.subjectType 2 diabetesen_US
dc.subjectAdiposityen_US
dc.subjectAge Factorsen_US
dc.subjectAgeden_US
dc.subjectBody Mass Indexen_US
dc.subjectChi-Square Distributionen_US
dc.subjectDiabetes Mellitus, Type 2en_US
dc.subjectFemaleen_US
dc.subjectHabitsen_US
dc.subjectHumansen_US
dc.subjectIncidenceen_US
dc.subjectLife Styleen_US
dc.subjectLogistic Modelsen_US
dc.subjectMaleen_US
dc.subjectMiddle Ageden_US
dc.subjectMultivariate Analysisen_US
dc.subjectOdds Ratioen_US
dc.subjectProspective Studiesen_US
dc.subjectRisk Assessmenten_US
dc.subjectRisk Factorsen_US
dc.subjectSleepen_US
dc.subjectTime Factorsen_US
dc.subjectUnited Kingdomen_US
dc.subjectWaist Circumferenceen_US
dc.titleDaytime napping, sleep duration and increased 8-year risk of type 2 diabetes in a British population.en_US
dc.typeArticle
dc.rights.holder2016 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University
dc.identifier.doi10.1016/j.numecd.2016.06.006en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/27484757en_US
pubs.issue11en_US
pubs.notesNo embargoen_US
pubs.publication-statusPublisheden_US
pubs.volume26en_US
dcterms.dateAccepted2016-06-17en_US


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