Now showing items 1-3 of 3
α-Actinin links extracellular matrix rigidity-sensing contractile units with periodic cell-edge retractions.
During spreading and migration, the leading edges of cells undergo periodic protrusion-retraction cycles. The functional purpose of these cycles is unclear. Here, using submicrometer polydimethylsiloxane pillars as substrates ...
Zebrafish Model for Functional Screening of Flow-Responsive Genes.
(Wolters Kluwer Health, Inc, 2016-11)
OBJECTIVE: Atherosclerosis is initiated at branches and bends of arteries exposed to disturbed blood flow that generates low shear stress. This mechanical environment promotes lesions by inducing endothelial cell (EC) ...
Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis.
(American Heart Association, Inc., 2017-07)
BACKGROUND: Myeloid cells are central to atherosclerotic lesion development and vulnerable plaque formation. Impaired ability of arterial phagocytes to uptake apoptotic cells (efferocytosis) promotes lesion growth and ...