Browsing Centre for Cancer Prevention by Issue Date
Now showing items 21-40 of 1006
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Viral pathophysiology of multiple sclerosis: A role for Epstein-Barr virus infection?
(2011-02)Multiple sclerosis (MS) is the most common inflammatory demyelinating and degenerative disease of the CNS. The cause of MS is unknown but environmental risk factors are implicated in MS. Several viruses have been proposed ... -
Small molecule chemokine mimetics suggest a molecular basis for the observation that CXCL10 and CXCL11 are allosteric ligands of CXCR3.
(2012-06)BACKGROUND AND PURPOSE: The chemokine receptor CXCR3 directs migration of T-cells in response to the ligands CXCL9/Mig, CXCL10/IP-10 and CXCL11/I-TAC. Both ligands and receptors are implicated in the pathogenesis of ... -
Dynamics of B-Cell Populations in CSF and Blood in Patients Treated with a Combination of Rituximab and Mitoxantrone.
(2013)Background. Mitoxantrone (MTX) and Rituximab (RTX) are successfully used for treatment of multiple sclerosis (MS) and can be combined to increase efficacy. Objective. We used MTX, RTX, and methylprednisolone in a single ... -
Skill set or mind set? Associations between health literacy, patient activation and health.
(2013)OBJECTIVE: There is ongoing debate on whether health literacy represents a skill-based construct for health self-management, or if it also more broadly captures personal 'activation' or motivation to manage health. This ... -
Analysing censored longitudinal data with non-ignorable missing values: Depression in older age
(2013-02-01)Missing values are common in cohort studies of the elderly. As part of a study of cognition in older age, we implemented a model for the analysis of longitudinal depression data complicated by the presence of non-ignorable ...