Now showing items 1-4 of 4

    • Chromosomal disorders: estimating baseline birth prevalence and pregnancy outcomes worldwide. 

      Moorthie, S; Blencowe, H; Darlison, MW; Gibbons, S; Lawn, JE; Mastroiacovo, P; Morris, JK; Modell, B; Congenital Disorders Expert Group (2018-10)
      Chromosomal disorders, of which Down syndrome is the most common, can cause multi-domain disability. In addition, compared to the general population, there is a higher frequency of death before the age of five. In many ...
    • Estimating the birth prevalence and pregnancy outcomes of congenital malformations worldwide. 

      Moorthie, S; Blencowe, H; Darlison, MW; Lawn, J; Morris, JK; Modell, B; Congenital Disorders Expert Group; Bittles, AH; Blencowe, H; Christianson, A (2018-10)
      Congenital anomaly registries have two main surveillance aims: firstly to define baseline epidemiology of important congenital anomalies to facilitate programme, policy and resource planning, and secondly to identify ...
    • Methods to estimate access to care and the effect of interventions on the outcomes of congenital disorders 

      Christianson, A; Cousens, S; Darlison, M; Gibbons, S; Hamamy, H; Khoshnood, B; Howson, CP; Lawn, JE; Mastroiacovo, P; Modell, B (2018-10-01)
      © 2018, The Author(s). In the absence of intervention, early-onset congenital disorders lead to pregnancy loss, early death, or disability. Currently, lack of epidemiological data from many settings limits the understanding ...
    • Rare single gene disorders: estimating baseline prevalence and outcomes worldwide 

      Blencowe, H; Moorthie, S; Petrou, M; Hamamy, H; Povey, S; Bittles, A; Gibbons, S; Darlison, M; Modell, B; Bittles, AH (2018-10-01)
      © 2018, The Author(s). As child mortality rates overall are decreasing, non-communicable conditions, such as genetic disorders, constitute an increasing proportion of child mortality, morbidity and disability. To date, ...