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Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.
(2009-06)
Translating a set of disease regions into insight about pathogenic mechanisms requires not only the ability to identify the key disease genes within them, but also the biological relationships among those key genes. Here ...
Prevalence of Posttraumatic Stress Disorder in Prisoners.
(2018-06-01)
People involved with criminal justice frequently are exposed to violence and traumatic experiences. This may lead to posttraumatic stress disorder (PTSD); however, no review, to our knowledge, has synthetized findings in ...
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.
(2017-03-21)
We have previously shown higher-than-expected rates of schizophrenia in relatives of patients with amyotrophic lateral sclerosis (ALS), suggesting an aetiological relationship between the diseases. Here, we investigate the ...
How to value patients with psychosis: An inductive study of psychiatrists’ behaviour in routine consultations.
(2015)
Valuing patients underlies good communication in psychiatry and mediates positive outcomes. The aim of this study was to (1) identify and reliably assess valuing and devaluing communicative behaviour of psychiatrists in ...
Weighted Burden Analysis of Exome-Sequenced Case-Control Sample Implicates Synaptic Genes in Schizophrenia Aetiology.
(2018-05)
A previous study of exome-sequenced schizophrenia cases and controls reported an excess of singleton, gene-disruptive variants among cases, concentrated in particular gene sets. The dataset included a number of subjects ...
Trauma proliferation and stress generation (TPSG) dynamics and their implications for clinical science.
(2018)
The current research and clinical focus on single traumas fails to assess numerous important trauma dynamics including trauma proliferation. In this study, 2 trauma proliferation pathways were identified that utilize a ...
Neurobehavioral effects of transportation noise in primary schoolchildren: a cross-sectional study.
(2010-06-01)
BACKGROUND: Due to shortcomings in the design, no source-specific exposure-effect relations are as yet available describing the effects of noise on children's cognitive performance. This paper reports on a study investigating ...
Social networks of patients with psychosis: a systematic review.
(2015-10-12)
BACKGROUND: Social networks are important for mental health outcomes as they can mobilise resources and help individuals to cope with social stressors. Individuals with psychosis may have specific difficulties in establishing ...
Mental health care for adult refugees in high-income countries.
(2018-04)
Approximately one-third of people who have obtained refugee status live in high-income countries. Over recent years, the number of refugees has been increasing, and there are questions on how many of them need mental health ...
Reporting participation rates in studies of non-pharmacological interventions for patients with chronic obstructive pulmonary disease: a systematic review.
(2012-12-29)
UNLABELLED: BACKGROUND: Pulmonary rehabilitation (PR) and self-management (SM) support programmes are effective in the management of patients with chronic obstructive pulmonary disease (COPD), but these interventions are ...