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Prenatal maternal plasma DNA screening for cystic fibrosis: A computer modelling study of screening performance.
Background: Prenatal cystic fibrosis (CF) screening is currently based on determining the carrier status of both parents. We propose a new method based only on the analysis of DNA in maternal plasma. Methods: The method ...
Prenatal reflex DNA screening for trisomies 21, 18, and 13.
PURPOSE: The purpose of the study was to determine the screening performance of prenatal reflex DNA screening for trisomies 21 (T21), 18 (T18), and 13 (T13) as part of a routine service at five hospitals. METHODS: Women ...