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Role of salt intake in prevention of cardiovascular disease: controversies and challenges.
(2018-06)
Strong evidence indicates that reduction of salt intake lowers blood pressure and reduces the risk of cardiovascular disease (CVD). The WHO has set a global target of reducing the population salt intake from the current ...
Qualitative analysis of feasibility of recruitment and retention in a planned randomised controlled trial of a psychosocial cancer intervention within the NHS.
(2018-06-22)
BACKGROUND: The randomised control trial (RCT) is the most rigorous method of evaluating interventions. Recruitment is often slower and more challenging than expected. The aim of the current paper is to understand the ...
Polygenic risk score for schizophrenia is not strongly associated with the expression of specific genes or gene sets.
(2018-08)
BACKGROUND: The polygenic risk score (PRS) is derived from single nucleotide polymorphisms (SNPs) including those that are genome-wide significant and also including a large number of others more weakly associated with ...
Community treatment orders in England: review of usage from national data.
(2018-06)
Aims and methodCommunity treatment orders (CTOs) have been in used in England and Wales since November 2008; however, their effectiveness has been debated widely, as has the question of which methodology is appropriate to ...
Mini-review: Update on the genetics of schizophrenia.
(2018-09)
A number of important findings have recently emerged relevant to identifying genetic risk factors for schizophrenia. Findings using common variants point towards gene sets of interest and also demonstrate an overlap with ...
What cervical screening is appropriate for women who have been vaccinated against high risk HPV? A simulation study.
(2018-02-15)
Women vaccinated against HPV16/18 are approaching the age for cervical screening; however, an updated screening algorithm has not been agreed. We use a microsimulation model calibrated to real published data to determine ...