Now showing items 1-10 of 29
The dose-response relationship between cigarette consumption, biochemical markers and risk of lung cancer.
The relationship between the number of cigarettes smoked per day and the incidence of lung cancer is linear but, from the multistage model of carcinogenesis, it should be quadratic (upwards curving). We investigated this ...
Specifying a Gold Standard for the Validation of Fetal Fraction Estimation in Prenatal Screening.
BACKGROUND: An estimate of fetal fraction (FF) is needed for DNA-based screening for trisomy 21 and other aneuploidies, but there is no gold standard to validate FF measurement methods. We specify a gold standard and use ...