Now showing items 1-10 of 24
Polygenic risk score for schizophrenia is not strongly associated with the expression of specific genes or gene sets.
BACKGROUND: The polygenic risk score (PRS) is derived from single nucleotide polymorphisms (SNPs) including those that are genome-wide significant and also including a large number of others more weakly associated with ...
Psychopathological Symptoms and Satisfaction with Mental Health in Patients with Schizophrenia.
BACKGROUND: The patient's view of their mental health is a central aspect in research and practice. Yet, little is known about which psychopathological symptoms are linked with patients' satisfaction with their mental ...
Satisfaction with sex life among patients with schizophrenia.
BACKGROUND: Whilst subjective quality of life has been extensively studied in patients with schizophrenia, little is known specifically about their satisfaction with their sex lives. Aim To assess the level of satisfaction ...
Association study of schizophrenia with variants in miR-137 binding sites.
There is strong cumulative evidence for the involvement of miR-137 and its targets in the aetiology of schizophrenia. Here we test whether variants, especially rare variants, in miR-137 binding sites are associated with ...
Polygenic risk score for schizophrenia is more strongly associated with ancestry than with schizophrenia.
BACKGROUND: The polygenic risk score (PRS) for schizophrenia, derived from very large numbers of weakly associated genetic markers, has been repeatedly shown to be robustly associated with schizophrenia in independent ...