Browsing Cell and Molecular Biology by Title
Now showing items 18-37 of 210
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Bacteria in Solitary Confinement
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Benznidazole-resistance in Trypanosoma cruzi is a readily acquired trait that can arise independently in a single population.
(2012-07-15)Benznidazole is the frontline drug used against Trypanosoma cruzi, the causative agent of Chagas disease. However, treatment failures are often reported. Here, we demonstrate that independently acquired mutations in the ... -
Big conductance calcium-activated potassium channel openers control spasticity without sedation.
(John Wiley and Sons, 2017-07-07)BACKGROUND AND PURPOSE: Our initial aim was to generate cannabinoid agents that control spasticity, occurring as a consequence of multiple sclerosis (MS), whilst avoiding the sedative side effects associated with cannabis. ... -
Bing-Neel Syndrome Case Report: A Previously Undocumented IgG Variant with MRI, PET/CT, and PET/MRI Imaging.
(2016)Waldenstrom's macroglobulinaemia is the most commonly reported subtype of lymphoplasmacytic lymphoma (LPL); it is characterised by IgM secretion. Neurological complications are common usually as a result of hyperviscosity. ... -
Can Dynamic Compression in the Absence of Growth Factors Induce Chondrogenic Differentiation of Bone Marrow Derived MSCs Encapsulated in Agarose Hydrogels?
(Springer Berlin Heidelberg, 2011)The objectives of this study were twofold; to determine if cartilage specific matrix synthesis by mesenchymal stem cells (MSCs) is regulated by the magnitude and/or duration of dynamic compression in the absence of growth ... -
Carbon in airway macrophages from children with asthma
(2014-01-01)Background: Airway macrophage (AM) phagocytosis is impaired in severe asthma. Prostaglandin (PG) E 2 and D 2 are increased in severe asthma and suppress AM phagocytic function in vitro. In this study, we sought evidence ... -
The Chicken Thigh Adductor Profundus Free Muscle Flap: A Novel Validated Non-Living Microsurgery Simulation Training Model.
(2017-07)BACKGROUND: Simulation training is becoming an increasingly important component of skills acquisition in surgical specialties, including Plastic Surgery. Non-living simulation models have an established place in Plastic ...