dc.contributor.author | McMullen, Heather | |
dc.date.accessioned | 2017-07-05T10:33:09Z | |
dc.date.available | 2017-07-05T10:33:09Z | |
dc.date.issued | 2017-03-15 | |
dc.date.submitted | 2017-07-05T10:41:06.090Z | |
dc.identifier.citation | McMullen, H. 2017. Health care innovations from policy to practice: A case study of a rapid HIV testing trial in general practice. Queen Mary University of London | en_US |
dc.identifier.uri | http://qmro.qmul.ac.uk/xmlui/handle/123456789/24712 | |
dc.description | PhD | en_US |
dc.description.abstract | The UK National Guidelines on HIV Testing 2008 recommended that adults in areas where
more than 2/1000 people were living with HIV be considered for an HIV test at the point of
registration with general practice. The RHIVA2 trial of rapid HIV testing in primary care
implemented and evaluated this recommendation across 20 general practices in a single UK
borough using a pragmatic cluster randomised controlled trial (RCT) design. This trial, and
the policy that underpinned it, reflected two more general developments: first, the move
towards population screening to detect and treat disease in early and latent stages and second,
the emergence of ‘pragmatic’ clinical trials that seek to account for complexity and measure
interventions in their context of use.
This interdisciplinary case study uses multiple methods and theoretical frames to explore
what happened in the RHIVA2 trial at both an empirical and a theoretical level. Sub-studies
reveal how the trial was justified, enacted and became meaningful as a policy, as a trial, and
as an intervention in the lives of patients. My analyses show that two operating logics
informed the justification and enactment of the trial and patterned patient and provider
experiences. The first, the logic of normalisation for HIV aims to treat HIV infection as a
medical condition ‘like any other’. This logic emphasises general practice as a site of
increased value and position in HIV management and as a space where population screening
can be undertaken. Second, the logic of the pragmatic trial aims to measure interventions in
the ‘real world’ but is revealed to produce unintended effects, raising questions about the
claims of such trials to generalisability and reproducibility.
This thesis demonstrates how contrasting versions of the research event (‘multiplicity’) can
be produced through different modes of inquiry, raising questions about the tension between
situated and generalisable findings. | en_US |
dc.description.sponsorship | National Institute of Health Research Doctoral training programme | en_US |
dc.language.iso | en | en_US |
dc.publisher | Queen Mary University of London | en_US |
dc.rights | The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the author | |
dc.subject | HIV | en_US |
dc.subject | rapid HIV testing | en_US |
dc.title | Health care innovations from policy to practice: A case study of a rapid HIV testing trial in general practice | en_US |
dc.type | Thesis | en_US |