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dc.contributor.authorPrzulj, Den_US
dc.contributor.authorHajek, Pen_US
dc.contributor.authorSnuggs, Sen_US
dc.contributor.authorMcRobbie, Hen_US
dc.date.accessioned2017-05-19T09:30:23Z
dc.date.available2017-05-11en_US
dc.date.issued2018-04-02en_US
dc.date.submitted2017-05-11T10:27:22.677Z
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/23178
dc.description.abstractIntroduction: Little is known about effects of smoking cessation on alcohol consumption. Varenicline reduces enjoyment of smoking and cigarette consumption and may also reduce enjoyment and consumption of alcohol. We conducted the first prospective examination of the effects of stopping smoking on alcohol enjoyment and consumption and compared clients using varenicline and nicotine replacement treatment (NRT). Methods: Audit of records from clients undergoing routine smoking cessation treatment in three stop-smoking services in London, United Kingdom. The sample comprised smokers who consume alcohol and underwent smoking cessation treatment with either varenicline (N = 230) or NRT (N = 62). Alcohol enjoyment and consumption were reported before and on the target quit day (TQD) and 1 and 4 weeks post-TQD. Results: Participants reduced their alcohol consumption in week 1 of their quit attempt (15.0-12.7 units per/week, p = .001).In heavy drinkers, the change remained significant at 4 weeks (32.2-24.8 units per/week, p = .004). The type of medication used had no significant impact on the change. Smokers treated with varenicline versus NRT were more likely to report reduced enjoyment of alcohol on TQD (20% vs. 10%, respectively, p < .001) and at 4 weeks post-TQD (20% vs. 6%, respectively, p = .014). Results were similar for abstainers and those who did not manage to stop smoking. Conclusion: Making a stop-smoking attempt is accompanied by a reduction in drinking. The finding has implications for policies concerned with effects of stopping smoking on alcohol use. Varenicline may affect enjoyment of drinking, but its potential to alter drinking behavior is small. Implications: The finding that smokers making a quit attempt reduce their alcohol consumption has practical implications for treatment providers who are concerned about the possible effects of smoking cessation on alcohol drinking. Although varenicline may reduce alcohol enjoyment compared to NRT, it does not appear to have a significant impact on alcohol consumption.en_US
dc.description.sponsorshipThis work was supported by a grant from Alcohol Research UK (SG 13/14 191).en_US
dc.format.extent583 - 588en_US
dc.languageengen_US
dc.language.isoenen_US
dc.relation.ispartofNicotine Tob Resen_US
dc.rightsThis is a pre-copyedited, author-produced version of an article accepted for publication in Nicotine and Tobacco Research following peer review. The version of record [Dunja Przulj, PhD, Peter Hajek, PhD, Sarah Snuggs, MSc, Hayden McRobbie, PhD; Changes in alcohol consumption during a stop-smoking attempt and differences between smokers using nicotine replacement and smokers using varenicline. Nicotine Tob Res 2017 ntx105. doi: 10.1093/ntr/ntx105] is available online at: https://doi.org/10.1093/ntr/ntx105
dc.titleChanges in Alcohol Consumption During a Stop-Smoking Attempt and Differences Between Smokers Using Nicotine Replacement and Smokers Using Varenicline.en_US
dc.typeArticle
dc.rights.holder© The Author 2017. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved.
dc.identifier.doi10.1093/ntr/ntx105en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/28521015en_US
pubs.issue5en_US
pubs.notes12 monthsen_US
pubs.publication-statusPublisheden_US
pubs.volume20en_US
dcterms.dateAccepted2017-05-11en_US


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