| dc.contributor.author | Gadelha, MR | en_US |
| dc.contributor.author | Kasuki, L | en_US |
| dc.contributor.author | Korbonits, M | en_US |
| dc.date.accessioned | 2017-03-21T13:34:07Z | |
| dc.date.available | 2017-01-03 | en_US |
| dc.date.issued | 2017-02 | en_US |
| dc.date.submitted | 2017-02-28T05:03:59.858Z | |
| dc.identifier.uri | http://qmro.qmul.ac.uk/xmlui/handle/123456789/21959 | |
| dc.description.abstract | Acromegaly is caused by a somatotropinoma in the vast majority of the cases. These are monoclonal tumors that can occur sporadically or rarely in a familial setting. In the last few years, novel familial syndromes have been described and recent studies explored the landscape of somatic mutations in sporadic somatotropinomas. This short review concentrates on the current knowledge of the genetic basis of both familial and sporadic acromegaly. | en_US |
| dc.format.extent | 10 - 21 | en_US |
| dc.language | eng | en_US |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Pituitary | en_US |
| dc.rights | “The final publication is available at Springer via http://dx.doi.org/10.1007/s11102-017-0789-7” | |
| dc.subject | AIP | en_US |
| dc.subject | Acromegaly | en_US |
| dc.subject | Familial disease | en_US |
| dc.subject | Genetic basis | en_US |
| dc.subject | Acromegaly | en_US |
| dc.subject | Female | en_US |
| dc.subject | Genetic Background | en_US |
| dc.subject | Growth Hormone-Secreting Pituitary Adenoma | en_US |
| dc.subject | Humans | en_US |
| dc.subject | Male | en_US |
| dc.subject | Mutation | en_US |
| dc.title | The genetic background of acromegaly. | en_US |
| dc.type | Article | |
| dc.rights.holder | (c) The Author(s) 2017. | |
| dc.identifier.doi | 10.1007/s11102-017-0789-7 | en_US |
| pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/28161730 | en_US |
| pubs.issue | 1 | en_US |
| pubs.notes | Not known | en_US |
| pubs.publication-status | Published | en_US |
| pubs.volume | 20 | en_US |
