• Login
    JavaScript is disabled for your browser. Some features of this site may not work without it.
    Cost-effectiveness of adherence therapy versus health education for people with schizophrenia: randomised controlled trial in four European countries. 
    •   QMRO Home
    • Blizard Institute
    • Centre for Primary Care and Public Health
    • Cost-effectiveness of adherence therapy versus health education for people with schizophrenia: randomised controlled trial in four European countries.
    •   QMRO Home
    • Blizard Institute
    • Centre for Primary Care and Public Health
    • Cost-effectiveness of adherence therapy versus health education for people with schizophrenia: randomised controlled trial in four European countries.
    ‌
    ‌

    Browse

    All of QMROCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects
    ‌
    ‌

    Administrators only

    Login
    ‌
    ‌

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Cost-effectiveness of adherence therapy versus health education for people with schizophrenia: randomised controlled trial in four European countries.

    View/Open
    Published version (354.7Kb)
    Volume
    11
    Pagination
    12 - ?
    DOI
    10.1186/1478-7547-11-12
    Journal
    Cost Eff Resour Alloc
    Issue
    1
    ISSN
    1478-7547
    Metadata
    Show full item record
    Abstract
    BACKGROUND: Non-adherence to anti-psychotics is common, expensive and affects recovery. We therefore examine the cost-effectiveness of adherence therapy for people with schizophrenia by multi-centre randomised trial in Amsterdam, London, Leipzig and Verona. METHODS: Participants received 8 sessions of adherence therapy or health education. We measured lost productivity and use of health/social care, criminal justice system and informal care at baseline and one year to estimate and compare mean total costs from health/social care and societal perspectives. Outcomes were the Short Form 36 (SF-36) mental component score (MCS) and quality-adjusted life years (QALYs) gained (SF-36 and EuroQoL 5 dimension (EQ5D)). Cost-effectiveness was examined for all cost and outcome combinations using cost-effectiveness acceptability curves (CEACs). RESULTS: 409 participants were recruited. There were no cost or outcome differences between adherence therapy and health education. The probability of adherence therapy being cost-effective compared to health education was between 0.3 and 0.6 for the six cost-outcome combinations at the willingness to pay thresholds we examined. CONCLUSIONS: Adherence therapy appears equivalent to health education. It is unclear whether it would have performed differently against a treatment as usual control, whether such an intervention can impact on quality of life in the short-term, or whether it is likely to be cost-effective in some sites but not others. TRIAL REGISTRATION: Trial registration: Current Controlled Trials ISRCTN01816159.
    Authors
    Patel, A; McCrone, P; Leese, M; Amaddeo, F; Tansella, M; Kilian, R; Angermeyer, M; Kikkert, M; Schene, A; Knapp, M
    URI
    http://qmro.qmul.ac.uk/xmlui/handle/123456789/17637
    Collections
    • Centre for Primary Care and Public Health [1629]
    Language
    eng
    Licence information
    This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
    Copyright statements
    n is available at the end of the article (c) 2013 Patel et al.; licensee BioMed Central Ltd.
    Twitter iconFollow QMUL on Twitter
    Twitter iconFollow QM Research
    Online on twitter
    Facebook iconLike us on Facebook
    • Site Map
    • Privacy and cookies
    • Disclaimer
    • Accessibility
    • Contacts
    • Intranet
    • Current students

    Modern Slavery Statement

    Queen Mary University of London
    Mile End Road
    London E1 4NS
    Tel: +44 (0)20 7882 5555

    © Queen Mary University of London.