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dc.contributor.authorWhite, PDen_US
dc.contributor.authorChalder, Ten_US
dc.contributor.authorSharpe, Men_US
dc.date.accessioned2016-09-09T11:49:18Z
dc.date.available2014-02-11en_US
dc.date.issued2015-02en_US
dc.date.submitted2016-08-19T15:40:36.302Z
dc.identifier.issn2056-4694en_US
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/15106
dc.description.abstractThe PACE trial was a four-arm trial of specialist medical care, compared with specialist medical care with a supplementary therapy: adaptive pacing therapy, cognitive-behavioural therapy or graded exercise therapy, for patients with chronic fatigue syndrome. The trial found that both cognitive-behavioural and graded exercise therapies were more effective than either of the other two treatments in reducing fatigue and improving physical disability. This paper describes the design, conduct and main results of the trial, along with a description of the challenges that had to be overcome in order to produce clear answers to the clinically important questions the trial posed.en_US
dc.description.sponsorshipThe funders of the PACE trial were: the Medical Research Council, the Department of Health (England), the Department for Work and Pensions, and the Chief Scientist Office (NHS Scotland).en_US
dc.format.extent24 - 27en_US
dc.languageengen_US
dc.relation.ispartofBJPsych Bullen_US
dc.rightsThis is an open-access article published by the Royal College of Psychiatrists and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/ licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleThe planning, implementation and publication of a complex intervention trial for chronic fatigue syndrome: the PACE trial.en_US
dc.typeArticle
dc.rights.holder(c) 2014 The Authors.
dc.identifier.doi10.1192/pb.bp.113.045005en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/26191420en_US
pubs.issue1en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.volume39en_US
dcterms.dateAccepted2014-02-11en_US
qmul.funderThe PACE trial; A RCT of CBT, graded exercise, adaptive pacing and usual medical care for the chronic fatigue syndrome::Medical Research Councilen_US


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