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dc.contributor.authorHerrett, Een_US
dc.contributor.authorGallagher, AMen_US
dc.contributor.authorBhaskaran, Ken_US
dc.contributor.authorForbes, Hen_US
dc.contributor.authorMathur, Ren_US
dc.contributor.authorvan Staa, Ten_US
dc.contributor.authorSmeeth, Len_US
dc.date.accessioned2016-08-05T12:50:46Z
dc.date.available2015-03-26en_US
dc.date.issued2015-06en_US
dc.date.submitted2016-07-13T11:33:20.548Z
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/13889
dc.description.abstractThe Clinical Practice Research Datalink (CPRD) is an ongoing primary care database of anonymised medical records from general practitioners, with coverage of over 11.3 million patients from 674 practices in the UK. With 4.4 million active (alive, currently registered) patients meeting quality criteria, approximately 6.9% of the UK population are included and patients are broadly representative of the UK general population in terms of age, sex and ethnicity. General practitioners are the gatekeepers of primary care and specialist referrals in the UK. The CPRD primary care database is therefore a rich source of health data for research, including data on demographics, symptoms, tests, diagnoses, therapies, health-related behaviours and referrals to secondary care. For over half of patients, linkage with datasets from secondary care, disease-specific cohorts and mortality records enhance the range of data available for research. The CPRD is very widely used internationally for epidemiological research and has been used to produce over 1000 research studies, published in peer-reviewed journals across a broad range of health outcomes. However, researchers must be aware of the complexity of routinely collected electronic health records, including ways to manage variable completeness, misclassification and development of disease definitions for research.en_US
dc.description.sponsorshipLS is supported by a Wellcome Trust Senior Research Fellowship in Clinical Science grant number 098504/Z/12/Z.en_US
dc.format.extent827 - 836en_US
dc.languageengen_US
dc.relation.ispartofInt J Epidemiolen_US
dc.rights© The Author 2015. Published by Oxford University Press on behalf of the International Epidemiological Association This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.subjectBiomedical Researchen_US
dc.subjectData Accuracyen_US
dc.subjectDatabases as Topicen_US
dc.subjectElectronic Health Recordsen_US
dc.subjectGeneral Practitionersen_US
dc.subjectHumansen_US
dc.subjectPrimary Health Careen_US
dc.subjectUnited Kingdomen_US
dc.titleData Resource Profile: Clinical Practice Research Datalink (CPRD).en_US
dc.typeArticle
dc.identifier.doi10.1093/ije/dyv098en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/26050254en_US
pubs.issue3en_US
pubs.notesNo embargoen_US
pubs.publication-statusPublisheden_US
pubs.volume44en_US
dcterms.dateAccepted2015-03-26en_US


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