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    Data Resource Profile: Clinical Practice Research Datalink (CPRD). 
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    Data Resource Profile: Clinical Practice Research Datalink (CPRD).

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    Published version (479.4Kb)
    Volume
    44
    Pagination
    827 - 836
    DOI
    10.1093/ije/dyv098
    Journal
    Int J Epidemiol
    Issue
    3
    Metadata
    Show full item record
    Abstract
    The Clinical Practice Research Datalink (CPRD) is an ongoing primary care database of anonymised medical records from general practitioners, with coverage of over 11.3 million patients from 674 practices in the UK. With 4.4 million active (alive, currently registered) patients meeting quality criteria, approximately 6.9% of the UK population are included and patients are broadly representative of the UK general population in terms of age, sex and ethnicity. General practitioners are the gatekeepers of primary care and specialist referrals in the UK. The CPRD primary care database is therefore a rich source of health data for research, including data on demographics, symptoms, tests, diagnoses, therapies, health-related behaviours and referrals to secondary care. For over half of patients, linkage with datasets from secondary care, disease-specific cohorts and mortality records enhance the range of data available for research. The CPRD is very widely used internationally for epidemiological research and has been used to produce over 1000 research studies, published in peer-reviewed journals across a broad range of health outcomes. However, researchers must be aware of the complexity of routinely collected electronic health records, including ways to manage variable completeness, misclassification and development of disease definitions for research.
    Authors
    Herrett, E; Gallagher, AM; Bhaskaran, K; Forbes, H; Mathur, R; van Staa, T; Smeeth, L
    URI
    http://qmro.qmul.ac.uk/xmlui/handle/123456789/13889
    Collections
    • Centre for Primary Care and Public Health [1467]
    Language
    eng
    Licence information
    © The Author 2015. Published by Oxford University Press on behalf of the International Epidemiological Association This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
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