Self-assembled nanoparticles as multifunctional drugs for anti-microbial therapies
7649 - 7649
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A self-assembled nanoparticle containing a photosensitizer and a Trojan-horse moiety (cholesterol), binds an anti-TB pro-drug and increases 1000-fold its activity against mycobacteria. These minimalist constructs will allow development of economically viable, efficient drug preparations for the treatment of drug-resistant TB infections.
AuthorsBhatti, M; McHugh, TD; Milanesi, L; Tomas, S
- College Publications