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Activity of oncolytic vaccinia virus vectors in ovarian cancer.
(Queen Mary University of London, 2012-03)
Oncolytic vaccinia virus has great potential in the treatment of cancer and two engineered
strains have entered clinical trials. As the advent for oncolytic vaccinia virus as an approved
therapy beckons, it is critical ...
Molecular Mechanisms of Lymphatic Invasion in Pancreatic Ductal Adenocarcinoma.
(Queen Mary University of London, 2012-05)
Pancreatic Ductal Adenocarcinoma (PDAC) is one of the five leading causes of cancer-related deaths in the West, and this, largely, is due to metastatic disease. In order to better understand PDAC metastatic spread and ...
Control of analgesic and anti-inflammatory pathways by fatty acid amide hydrolase
(Queen Mary University of London, 2012)
The endogenous cannabinoids (endocannabinoids) arachidonoyl ethanolamide (AEA)
and 2-arachidonoyl glycerol (2-AG) regulate neurotransmission and inflammation by
activating the CB1 cannabinoid receptors in the central ...