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Neurodegeneration progresses despite complete elimination of clinical relapses in a mouse model of multiple sclerosis.
BACKGROUND: [corrected] Multiple Sclerosis has two clinical phases reflecting distinct but inter-related pathological processes: focal inflammation drives the relapse-remitting stage and neurodegeneration represents the ...
Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis.
Autoimmunity to neuronal proteins occurs in several neurological syndromes, where cellular and humoral responses are directed to surface as well as intracellular antigens. Similar to myelin autoimmunity, pathogenic immune ...