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Neurodegeneration progresses despite complete elimination of clinical relapses in a mouse model of multiple sclerosis.
(2013-12-23)
BACKGROUND: [corrected] Multiple Sclerosis has two clinical phases reflecting distinct but inter-related pathological processes: focal inflammation drives the relapse-remitting stage and neurodegeneration represents the ...
Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis.
(2013)
Autoimmunity to neuronal proteins occurs in several neurological syndromes, where cellular and humoral responses are directed to surface as well as intracellular antigens. Similar to myelin autoimmunity, pathogenic immune ...
Neurofilament light as an immune target for pathogenic antibodies.
(2017-12)
Antibodies to neuronal antigens are associated with many neurological diseases including paraneoplastic neurological disorders, epilepsy, amyotrophic lateral sclerosis and multiple sclerosis. Immunization with neuronal ...