Search
Now showing items 661-670 of 673
Skin-resident innate lymphoid cells converge on a pathogenic effector state.
(2021-04)
Tissue-resident innate lymphoid cells (ILCs) help sustain barrier function and respond to local signals. ILCs are traditionally classified as ILC1, ILC2 or ILC3 on the basis of their expression of specific transcription ...
Targeted molecular profiling of rare olfactory sensory neurons identifies fate, wiring, and functional determinants
(eLife Sciences Publications, 2021-03-05)
Determining the molecular properties of neurons is essential to understand their development, function and evolution. Using Targeted DamID (TaDa), we characterize RNA polymerase II occupancy and chromatin accessibility in ...
The hippocampus and orbitofrontal cortex jointly represent task structure during memory-guided decision making
(Cell Press, 2021-11-30)
The hippocampus, well known for its role in episodic memory, might also be an important brain region for extracting structure from our experiences in order to guide future decisions. Recent evidence in rodents suggests ...
Forgetting emotional material in working memory
(Oxford University Press, 2017-12-20)
Proactive interference (PI) is the tendency for information learned earlier to interfere with more recently learned information. In the present study, we induced PI by presenting items from the same category over several ...
Tall stature and gigantism in adult patients with acromegaly.
(2024-03-02)
OBJECTIVES: Increased height in patients with acromegaly could be a manifestation of growth hormone (GH) excess before epiphysis closure. The aim of this study was to evaluate the relationship between the height of adult ...
Risk of fractures in half a million survivors of 20 cancers: a population-based matched cohort study using linked English electronic health records.
(2024-03)
BACKGROUND: A history of multiple myeloma, prostate cancer, and breast cancer has been associated with adverse bone health, but associations across a broader range of cancers are unclear. We aimed to compare the risk of ...
Cell-type specialization is encoded by specific chromatin topologies.
(2021-11)
The three-dimensional (3D) structure of chromatin is intrinsically associated with gene regulation and cell function1-3. Methods based on chromatin conformation capture have mapped chromatin structures in neuronal systems ...
A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina.
(2023-12-21)
BACKGROUND: Percutaneous coronary intervention (PCI) is frequently performed to reduce the symptoms of stable angina. Whether PCI relieves angina more than a placebo procedure in patients who are not receiving antianginal ...
Work hours, weekend working, nonstandard work schedules and sleep quantity and quality: findings from the UK household longitudinal study.
(2024-01-27)
BACKGROUND: Atypical temporal work patterns such as working longer than the standard 35-40 h/ week, weekend working, and nonstandard work schedules (i.e. outside of the typical 9-5, including but not restricted to shiftwork) ...
The effects of consuming eggs for lunch on satiety and subsequent food intake.
(2011-09)
The aim of the present work was to investigate the effects of eggs consumed for lunch on satiety, satiation and subsequent energy intake at the next meal. Thirty-one healthy male and female subjects participated in a ...