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Degradation pattern of a porcine collagen membrane in an in vivo model of guided bone regeneration.
(2018-06)
BACKGROUND AND OBJECTIVE: Although collagen membranes have been clinically applied for guided tissue/bone regeneration for more than 30 years, their in vivo degradation pattern has never been fully clarified. A better ...
Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms.
(2015-05-15)
PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) is a cancer of the exocrine pancreas with unmet medical need and is strongly promoted by tumor-associated macrophages (TAM). The presence of TAMs is associated with poor ...
Bioactive Glasses: Sprouting Angiogenesis in Tissue Engineering.
(Elsevier (Cell Press), 2018-03-05)
The biggest strategic challenge for tissue engineering is the development of efficient vascularized networks in engineered tissues and organs. Bioactive glasses (BGs) are potent biomaterials for inducing angiogenesis in ...
Counteractive effects of antenatal glucocorticoid treatment on D1 receptor modulation of spatial working memory.
(2016-10)
RATIONALE: Antenatal exposure to the glucocorticoid dexamethasone dramatically increases the number of mesencephalic dopaminergic neurons in rat offspring. However, the consequences of this expansion in midbrain dopamine ...
Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids.
(2014-02)
Protein kinase C iota (PKCι), a serine/threonine kinase required for cell polarity, proliferation and migration, is commonly up- or downregulated in cancer. PKCι is a human oncogene but whether this is related to its role ...
Sorting live stem cells based on Sox2 mRNA expression.
(2012)
While cell sorting usually relies on cell-surface protein markers, molecular beacons (MBs) offer the potential to sort cells based on the presence of any expressed mRNA and in principle could be extremely useful to sort ...
Resources alter the structure and increase stochasticity in bromeliad microfauna communities.
(2015)
Although stochastic and deterministic processes have been found to jointly shape structure of natural communities, the relative importance of both forces may vary across different environmental conditions and across levels ...
Lasting effects of maternal behaviour on the distribution of a dispersive stream insect.
(2011-09)
1. Predicting population dynamics at large spatial scales requires integrating information about spatial distribution patterns, inter-patch movement rates and within-patch processes. Advective dispersal of aquatic species ...
Integrating evolution into ecological modelling: accommodating phenotypic changes in agent based models.
(2013)
Evolutionary change is a characteristic of living organisms and forms one of the ways in which species adapt to changed conditions. However, most ecological models do not incorporate this ubiquitous phenomenon. We have ...
The Trypanosoma cruzi vitamin C dependent peroxidase confers protection against oxidative stress but is not a determinant of virulence.
(2015-04)
BACKGROUND: The neglected parasitic infection Chagas disease is rapidly becoming a globalised public health issue due to migration. There are only two anti-parasitic drugs available to treat this disease, benznidazole and ...