Now showing items 561-564 of 564
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
(Nature Research (part of Springer Nature), 2019-03-29)
The concentrations of high- and low-density-lipoprotein cholesterol and triglycerides are influenced by smoking, but it is unknown whether genetic associations with lipids may be modified by smoking. We conducted a ...
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
(Nature Research (part of Springer Nature), 2019-01-22)
Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects. To identify lipid loci interacting with physical activity, we ...
Social support, social network and salt-reduction behaviours in children: a sub-study of the School-EduSalt trial
(BMJ Journals, 2019-06-14)
OBJECTIVES: Healthy behaviour changes, such as reducing salt intake, are important to prevent lifestyle-related diseases. Social environment is a major challenge to achieve such behaviours, but the explicit mechanisms ...
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
(Oxford University Press (OUP), 2019-04-10)
Elevated blood pressure (BP), a leading cause of global morbidity and mortality, is influenced by both genetic and lifestyle factors. Cigarette smoking is one such lifestyle factor. Across five ancestries, we performed a ...