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Ischaemic and Pharmacological Preconditioning of the Uraemic Heart.
(Queen Mary University of London, 2011)
The incidence and mortality from cardiovascular disease (CVD) in patients with
chronic kidney disease (CKD) far exceeds that seen in the general population.
Whilst a number of risk factors and associations have been ...
Promoting the survival, migration and integration of Schwann cells by over-expression of polysialic acid
(2011)
The poor survival and migration of transplanted Schwann cells (SCs) are major drawbacks for their clinical application in cell therapy for neurotrauma. To overcome such drawbacks we genetically modified SCs to over-express ...
Prenatal identification of trisomy 18 (Edwards syndrome)
(2011)
This thesis provides a literature review of trisomy 18 (Edwards syndrome) with a focus
on the use of maternal serum and ultrasound markers in the late first and early second
trimester of pregnancy to aid in identifying ...
Primary tissue-based proteomic analysis of apoptosis-regulating pathways in malignant pleural mesothelioma (MPM)
(2011)
Malignant pleural mesothelioma (MPM) is an aggressive and fatal malignancy associated with resistance to chemotherapy and radiotherapy. Programmed cell death or apoptosis underlies the efficacy of cytotoxic anti-cancer ...
Optimal Relaxed Designs of Experiments, with Pharmaceutical Applications
(Queen Mary University of London, 2014-06)
This thesis was motivated by the collaborative research undertaken by QMUL and Pfizer UK
into improving experiments at pre-clinical drug development. In theory, the most efficient
designs for these particular experiments, ...
Burden of neglected tropical diseases and access to medicine and diagnostics in Ethiopia: a scoping review.
(2023-08-14)
BACKGROUND: More than 1.7 billion people are affected by neglected tropical diseases (NTDs) worldwide. Forty percent of the NTD-affected people live in Africa with the poorest, most vulnerable, and hard to reach geographical ...
Corporate rescues - a comparative study of the law and procedure in Australia, Canada and England
(Queen Mary University of London, 1995)
Corporate insolvency law reform in the mid 80's in the United Kingdom and the early
90's in Canada and Australia resulted in the introduction of new statutory regimes directed
specifically towards facilitating the rescue ...
