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Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses.

Bullen, G; Galson, JD; Hall, G; Villar, P; Moreels, L; Ledsgaard, L; Mattiuzzo, G; Bentley, EM; Masters, EW; Tang, D;... (Frontiers Media, 2021-06-15)

Passive immunization using monoclonal antibodies will play a vital role in the fight against COVID-19. The recent emergence of viral variants with reduced sensitivity to some current antibodies and vaccines highlights the ...

A retrospective cohort study of risk factors and outcomes in older patients admitted to an inner-city geriatric unit in London during first peak of COVID-19 pandemic.

Maniero, C; Patel, D; Pavithran, A; Naran, P; Ng, FL; Prowle, J; Sivapathasuntharam, D (2021-07-06)

PURPOSE: Compared to younger patients, coronavirus disease 2019 (COVID-19) clinical presentation in older people can be more heterogeneous and fatal. We aim to describe a cohort of older adults admitted in an inner-city ...

"We also deserve help during the pandemic": The effect of the COVID-19 pandemic on foreign domestic workers in Hong Kong.

Lui, ID; Vandan, N; Davies, SE; Harman, S; Morgan, R; Smith, J; Wenham, C; Grépin, KA (2021)

The coronavirus disease 2019 (COVID-19) pandemic poses particular challenges for migrant workers around the world. This study explores the unique experiences of foreign domestic workers (FDWs) in Hong Kong, and how COVID-19 ...

Rapid, early and accurate SARS-CoV-2 detection using RT-qPCR in primary care: a prospective cohort study (REAP-1).

Leber, W; Lammel, O; Redlberger-Fritz, M; Mustafa-Korninger, ME; Glehr, RC; Camp, J; Agerer, B; Lercher, A; Popa, A; Genger, J-W;... (2021-08-02)

OBJECTIVES: We explore the importance of SARS-CoV-2 sentinel surveillance testing in primary care during a regional COVID-19 outbreak in Austria. DESIGN: Prospective cohort study. SETTING: A single sentinel practice serving ...

COVID-19: Causes of anxiety and wellbeing support needs of healthcare professionals in the UK: A cross-sectional survey.

Siddiqui, I; Aurelio, M; Gupta, A; Blythe, J; Khanji, MY (Royal College of Physicians, 2021-01)

BACKGROUND: COVID-19 has caused acute changes in healthcare delivery; this may impact mental health and wellbeing needs of healthcare professionals (HCPs). AIMS: We aimed to identify the causes of anxiety in HCPs during ...

Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients.

Palmas, F; Clarke, J; Colas, RA; Gomez, EA; Keogh, A; Boylan, M; McEvoy, N; McElvaney, OJ; McElvaney, O; Alalqam, R;... (Public Library of Science, 2021-08-26)

Coronavirus disease (COVID)-19, as a result of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, has been the direct cause of over 2.2 million deaths worldwide. A timely coordinated host-immune response ...

Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial.

Arabi, YM; Gordon, AC; Derde, LPG; Nichol, AD; Murthy, S; Beidh, FA; Annane, D; Swaidan, LA; Beane, A; Beasley, R;... (2021-07-12)

PURPOSE: To study the efficacy of lopinavir-ritonavir and hydroxychloroquine in critically ill patients with coronavirus disease 2019 (COVID-19). METHODS: Critically ill adults with COVID-19 were randomized to receive ...

Treatment of Women with Multiple Sclerosis Planning Pregnancy

Krysko, KM; Bove, R; Dobson, R; Jokubaitis, V; Hellwig, K (2021-04)

Maintenance therapy with infliximab or vedolizumab in IBD is not associated with increased SARS-CoV-2 seroprevalence: UK experience in the 2020 pandemic.

McGregor, CG; Adams, A; Sadler, R; Arancibia-Cárcamo, CV; Palmer, R; Ambrose, T; Brain, O; Walsh, A; Klenerman, P; Travis, SP;... (2021-02-12)

Childhood asthma outcomes during the COVID-19 pandemic: Findings from the PeARL multi-national cohort.

Papadopoulos, NG; Mathioudakis, AG; Custovic, A; Deschildre, A; Phipatanakul, W; Wong, G; Xepapadaki, P; Abou-Taam, R; Agache, I; Castro-Rodriguez, JA;... (2021-06)

BACKGROUND: The interplay between COVID-19 pandemic and asthma in children is still unclear. We evaluated the impact of COVID-19 pandemic on childhood asthma outcomes. METHODS: The PeARL multinational cohort included 1,054 ...

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