Now showing items 1371-1380 of 1626
Viral hepatitis and Parkinson disease: A national record-linkage study.
(American Academy of Neurology, 2017-03-29)
OBJECTIVE: To study associations between viral hepatitis and Parkinson disease (PD). METHODS: A retrospective cohort study was done by analyzing linked English National Hospital Episode Statistics and mortality data ...
Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1.
(BioMed Central Ltd., 2014-01-04)
BACKGROUND: Recently, genome-wide association studies (GWAS) for cases versus controls using single nucleotide polymorphism microarray data have shown promising findings for complex neuropsychiatric disorders, including ...
Super-recognition in development: A case study of an adolescent with extraordinary face recognition skills.
(Taylor and Francis, 2017-11)
Face recognition abilities vary widely. While face recognition deficits have been reported in children, it is unclear whether superior face recognition skills can be encountered during development. This paper presents O.B., ...
PTX3, a humoral pattern recognition molecule at the interface between microbe and matrix recognition.
Innate immunity consists of a cellular and a humoral arm. PTX3 is a fluid patter recognition molecule (PRM) with antibody-like properties. Gene targeted mice and genetic associations in humans suggest that PTX3 plays a ...
Randomised trial of text messaging on adherence to cardiovascular preventive treatment (INTERACT trial).
(PLoS ONE, 2014-12-05)
BACKGROUND: About one third of patients prescribed blood pressure or lipid-lowering drugs for the prevention of coronary heart disease and stroke do not take their medication as prescribed. We conducted a randomized trial ...
KIR content genotypes associate with carriage of hepatitis B surface antigen, e antigen and HBV viral load in Gambians.
(Public Library of Science, 2017-11-17)
BACKGROUND: Hepatocellular carcinoma (HCC) causes over 800,000 deaths worldwide annually, mainly in low income countries, and incidence is rising rapidly in the developed world with the spread of hepatitis B (HBV) and C ...
Evaluating the glucose raising effect of established loci via a genetic risk score.
Recent genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) associated with glucose levels. We tested the hypothesis here whether the cumulative effect of glucose raising SNPs, ...
Lessons from the Iraq war: more aggressive peace building needed.
Randomised controlled trial and economic evaluation of the 'Families for Health' programme to reduce obesity in children.
(BMJ Publishing Group, 2017-04-19)
OBJECTIVE: Evaluating effectiveness and cost-effectiveness of 'Families for Health V2' (FFH) compared with usual care (UC). DESIGN: Multicentre randomised controlled trial (RCT) (investigators blinded, families unblinded) ...
The Sharing Experimental Animal Resources, Coordinating Holdings (SEARCH) Framework: Encouraging Reduction, Replacement, and Refinement in Animal Research.
(Public Library of Science, 2017-01-12)
While significant medical breakthroughs have been achieved through using animal models, our experience shows that often there is surplus material remaining that is frequently never revisited but could be put to good use ...