Search
Now showing items 1-4 of 4
Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.
(2018-08-06)
Cholesterol homeostasis has a pivotal function in regulating immune cells. Here we show that apolipoprotein E (apoE) deficiency leads to the accumulation of cholesterol in the cell membrane of dendritic cells (DC), resulting ...
Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane.
(2003-03-17)
We have demonstrated previously that adult human synovial membrane-derived mesenchymal stem cells (hSM-MSCs) have myogenic potential in vitro (De Bari, C., F. Dell'Accio, P. Tylzanowski, and F.P. Luyten. 2001. Arthritis ...
Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues.
(2016-03-21)
KRAB-containing zinc finger proteins (KRAB-ZFPs) are early embryonic controllers of transposable elements (TEs), which they repress with their cofactor KAP1 through histone and DNA methylation, a process thought to result ...
Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses.
(2016-08-24)
Resolution of inflammation is a finely regulated process mediated by specialized proresolving lipid mediators (SPMs), including docosahexaenoic acid (DHA)-derived resolvins and maresins. The immunomodulatory role of SPMs ...