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Molecular Mechanisms of Lymphatic Invasion in Pancreatic Ductal Adenocarcinoma.
(Queen Mary University of London, 2012-05)
Pancreatic Ductal Adenocarcinoma (PDAC) is one of the five leading causes of cancer-related deaths in the West, and this, largely, is due to metastatic disease. In order to better understand PDAC metastatic spread and ...
The role of epithelial cell-derived tumour necrosis Factor Alpha in pancreatic carcinogenesis
(Queen Mary University of London, 2012-03)
Activating mutations of the kras proto-oncogene are found in more than 90 % of human pancreatic ductal adenocarcinoma (PDAC) and can result in increased activity of the NF-κB pathway, leading to constitutive production ...