Now showing items 1-1 of 1
Identification of novel therapeutics for the treatment of MMR deficient tumours using high-throughput screens.
(Queen Mary University of London, 2015-05)
The DNA Mismatch repair (MMR) pathway is responsible for the repair of base-base mismatches and insertion/deletion loops, formed during DNA replication. Mutations in MMR genes significantly increase the predisposition to ...