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Identification of novel therapeutics for the treatment of MMR deficient tumours using high-throughput screens.
(Queen Mary University of London, 2015-05)
The DNA Mismatch repair (MMR) pathway is responsible for the repair of base-base mismatches and insertion/deletion loops, formed during DNA replication. Mutations in MMR genes significantly increase the predisposition to ...
Measurement of the production cross section of a W boson with a single charm quark using the ATLAS detector at the Large Hadron Collider.
(Queen Mary University of London, 2014)
This thesis presents the measurement of the production cross section of a W boson with a single charm quark in 7 TeV proton-proton collisions using the ATLAS
detector at the Large Hadron Collider. The data analysed ...