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Exosomes derived from embryonal and alveolar rhabdomyosarcoma carry differential miRNA cargo and promote invasion of recipient fibroblasts.

Ghayad, SE; Rammal, G; Ghamloush, F; Basma, H; Nasr, R; Diab-Assaf, M; Chelala, C; Saab, R (2016-11-17)

Rhabdomyosarcoma (RMS) is an aggressive childhood soft tissue tumor, which exists in oncoprotein PAX-FOXO1 fusion positive and fusion negative subtypes, with the fusion-positive RMS being characterized by a more aggressive ...