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Atypical risk factor profile and excellent long-term outcomes of young patients treated with primary percutaneous coronary intervention for ST-elevation myocardial infarction.

Rathod, KS; Jones, DA; Gallagher, S; Rathod, VS; Weerackody, R; Jain, AK; Mathur, A; Mohiddin, SA; Archbold, RA; Wragg, A;... (2016-02)

INTRODUCTION: Several studies have examined the relationship between age and clinical outcomes in patients with ST-elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PPCI). The ...

Importance of primary percutaneous coronary intervention for reducing mortality in ST-elevation myocardial infarction complicated by out of hospital cardiac arrest.

Choudry, FA; Weerackody, RP; Timmis, AD; Wragg, A; Mathur, A; Sporton, S; Mills, PG; Jain, AK (2015-08)

BACKGROUND: Current recommendations are for primary percutaneous coronary intervention (pPCI) in ST-elevation myocardial infarction (STEMI) complicated by out of hospital cardiac arrest (OHCA). However, information about ...

Does a 'direct' transfer protocol reduce time to coronary angiography for patients with non-ST-elevation acute coronary syndromes? A prospective observational study.

Gallagher, SM; Lovell, MJ; Jones, DA; Ferguson, E; Ahktar, A; Buckhoree, Z; Wragg, A; Knight, CJ; Mathur, A; Smith, EJ;... (2014-09-29)

OBJECTIVE: National guidelines recommend 'early' coronary angiography within 96 h of presentation for patients with non-ST elevation acute coronary syndromes (NSTE-ACS). Most patients with NSTE-ACS present to their district ...

Outcomes after chronic total occlusion percutaneous coronary interventions: an observational study of 5496 patients from the Pan-London CTO Cohort.

Jones, DA; Rathod, KS; Pavlidis, AN; Gallagher, SM; Astroulakis, Z; Lim, P; Sirker, A; Knight, CJ; Dalby, MC; Malik, IS;... (2018-11)

BACKGROUND: Chronic total occlusions (CTO) are commonly encountered in patients undergoing coronary angiography; however, percutaneous coronary intervention (PCI) is infrequently performed owing to technical difficulty, ...

Neointima and neoatherosclerotic characteristics in bare metal and first- and second-generation drug-eluting stents in patients admitted with cardiovascular events attributed to stent failure: an optical coherence tomography study.

Stettler, R; Dijkstra, J; Räber, L; Torii, R; Zhang, Y-J; Karanasos, A; Lui, S; Crake, T; Hamshere, S; Garcia-Garcia, HM;... (2018-02-02)

AIMS: The aim of this study was to assess neoatherosclerotic plaque morphology in bare metal (BMS) and first- and second-generation drug-eluting stents (DES) in patients presenting with an event attributed to stent failure. ...

Mineralocorticoid receptor antagonist pretreatment to MINIMISE reperfusion injury after ST-elevation myocardial infarction (the MINIMISE STEMI Trial): rationale and study design.

Bulluck, H; Fröhlich, GM; Mohdnazri, S; Gamma, RA; Davies, JR; Clesham, GJ; Sayer, JW; Aggarwal, RK; Tang, KH; Kelly, PA;... (2015-05)

Novel therapies capable of reducing myocardial infarct (MI) size when administered prior to reperfusion are required to prevent the onset of heart failure in ST-segment elevation myocardial infarction (STEMI) patients ...

Potential economic consequences of a cardioprotective agent for patients with myocardial infarction: modelling study.

Verhoef, TI; Morris, S; Mathur, A; Singer, M (2015-11-13)

OBJECTIVE: To investigate the cost-effectiveness of a hypothetical cardioprotective agent used to reduce infarct size in patients undergoing percutaneous coronary intervention (PCI) after anterior ST-elevation myocardial ...

Risk scoring to guide antiplatelet therapy post-percutaneous coronary intervention for acute coronary syndrome results in improved clinical outcomes.

Antoniou, S; Colicchia, M; Guttmann, OP; Rathod, KS; Wright, P; Fhadil, S; Knight, CJ; Jain, AK; Smith, EJ; Mathur, A;... (2018-10-01)

Aims: To use the Global Registry of Acute Coronary Events (GRACE) and Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines (CRUSADE) scores ...

Intravascular multimodality imaging: feasibility and role in the evaluation of coronary plaque pathology.

Michail, M; Serruys, PW; Stettler, R; Crake, T; Torii, R; Tenekecioglu, E; Zeng, Y; Onuma, Y; Mathur, A; Bourantas, CV (Oxford University Press, 2017-02-17)

Coronary artery disease remains the leading cause of death in the developed world. Over recent years, research has been focused on the development of diagnostic intravascular imaging techniques that enable assessment of ...

Angiography Alone Versus Angiography Plus Optical Coherence Tomography to Guide Percutaneous Coronary Intervention: Outcomes From the Pan-London PCI Cohort.

Jones, DA; Rathod, KS; Koganti, S; Hamshere, S; Astroulakis, Z; Lim, P; Sirker, A; O'Mahony, C; Jain, AK; Knight, CJ;... (2018-07-23)

OBJECTIVES: This study aimed to determine the effect on long-term survival of using optical coherence tomography (OCT) during percutaneous coronary intervention (PCI). BACKGROUND: Angiographic guidance for PCI has substantial ...