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‘So you feel a bit anxious?’ Psychiatrist-patient communication and treatment adherence in schizophrenia
(Queen Mary University of London, 2013-09)
24 million people worldwide are affected by schizophrenia. Its complex psychopathology,
including changes in perception, can incur substantial personal distress and economic burden.
Finding appropriate treatment that ...
The trauma of trauma: a prospective study of psychological distress following physical injury.
(Queen Mary University of London, 2015-05)
Background: People who experience physical trauma face a range of psychosocial outcomes. These may be overlooked by busy clinicians. While some risk factors are understood, our understanding of the psychological effects ...
The role of cytokines and the suppressors of cytokine signalling (SOCS) in human osteoblastic cell survival and bone remodelling.
(Queen Mary University of London, 2012)
A number of growth factors and cytokines involved in the local regulation of bone
remodelling are either synthesised by osteoblasts or have osteoblasts as their target.
These include the RANK-L/OPG system, the gp130 ...
The role of chemistry and strut porosity and the influence of serum proteins in modulating cellular response to bone graft substitutes
(Queen Mary University of London, 23/02/2015)
The objective of this thesis was to investigate the role of hydroxyapatite and silicate-substituted hydroxyapatite synthetic bone graft substitute (SBG) material properties in modulating the processes of protein adsorption ...
Evaluation of the anti-tumour potency and biodistribution of vaccinia virus mutants in solid tumour models
(Queen Mary University of London, 2013)
The survival of many patients with advanced solid tumours has remained poor over the past 40 years, despite improvements in existing therapies. Progress in the field of molecular biology has made gene therapy a feasible ...
