Search
Now showing items 1-6 of 6
Novel cardioprotective strategies for the uraemic heart.
(Queen Mary University of London, 2011)
Cardiovascular disease is the leading cause of death in patients with underlying chronic
kidney disease (CKD). Up to one third of patients presenting with an acute coronary
syndrome have CKD stage 3-5. Outcomes following ...
Investigation of the effect of inorganic nitrate on platelet and endothelial function in healthy individuals and in patients with hypercholesterolaemia.
(Queen Mary University of London, 2014)
Ingestion of vegetables rich in inorganic nitrate (NO3-) content has emerged as an effective method, via the formation of a nitrite (NO2-) intermediate, for acutely elevating vascular nitric oxide (NO) levels. As such a ...
A functional study of ADAMTS7 gene variants.
(Queen Mary University of London, 2014-03)
Background: Recent studies have revealed an association between genetic variants at the
ADAMTS7 (a disintegrin-like and metalloprotease with thrombospondin type 1 motif, 7)
locus and susceptibility to coronary artery ...
Non-Regenerative Benefits of Adult Bone Marrow Derived Stem Cells for Myocardial Protection
(Queen Mary University of London, 2013)
Ischaemic heart disease is the most common cause of mortality in the
western hemisphere and it is rapidly becoming the leading cause of death
globally. Moreover, therapeutic interventions by cardiologists and cardiac
surgeons ...
Insights into molecular and functional mechanisms behind inherited heart and skin disorders.
(Queen Mary University of London, 2015-03)
Desmosomes are macromolecular, dynamic and adaptable complexes that connect intermediate filaments of neighboring cells in a variety of tissues, generating a large mechanically resilient structure. The importance of ...
Catheter ablation of fractionated electrograms for atrial fibrillation: does it improve outcomes and can it be refined based on electrogram morphology or knowledge of the remodelling process?.
(Queen Mary University of London, 2013)
Catheter ablation complex or fractionated atrial electrograms (CFAE) may improve outcomes for persistent AF. However, it is unclear whether CFAE are important in maintaining AF or whether targeting of CFAE can be refined ...
