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Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.

Bilanges, B; Alliouachene, S; Pearce, W; Morelli, D; Szabadkai, G; Chung, Y-L; Chicanne, G; Valet, C; Hill, JM; Voshol, PJ;... (2017-11-27)

Vps34 PI3K is thought to be the main producer of phosphatidylinositol-3-monophosphate, a lipid that controls intracellular vesicular trafficking. The organismal impact of systemic inhibition of Vps34 kinase activity is not ...