Search
Now showing items 1-4 of 4
Exploring biomarkers from the tumour and the microenvironment in Diffuse Large B-cell Lymphoma.
(Queen Mary University of London, 2014-11)
In the last decade unprecedented improvement in cure rates and overall survival was achieved in diffuse large B-cell Lymphoma (DLBCL) through the introduction of rituximab and anthracyclin-based chemotherapy (R-CHOP) as ...
The defects underlying impaired T-cell immunity in chronic lymphocytic leukaemia: the impact of lenalidomide
(Queen Mary University of London, 2013-07)
CLL T cells exhibit functional defects and alterations in gene expression that show similarities to exhausted T cells in chronic viral infections. It is unclear whether CLL T cells are truly exhausted, or whether these ...
Development of a framework to improve rehabilitation and health outcome in major trauma patients and trauma systems.
(Queen Mary University of London, 2015)
Rehabilitation outcomes are an important measurement of trauma system effectiveness. However, currently there is no clinically applicable trauma rehabilitation score or framework available to evaluate health and rehabilitation ...
Characterising the tumour evolution and genetic heterogeneity underlying follicular lymphoma and its progression.
(Queen Mary University of London, 2015-04)
Follicular lymphoma (FL) is an incurable indolent non-Hodgkin’s lymphoma (NHL) that behaves heterogeneously. Although epitomised by the t(14;18), the full spectrum of genetic lesions and the clonal hierarchy that contribute ...