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Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane.

De Bari, C; Dell'Accio, F; Vandenabeele, F; Vermeesch, JR; Raymackers, J-M; Luyten, FP (2003-03-17)

We have demonstrated previously that adult human synovial membrane-derived mesenchymal stem cells (hSM-MSCs) have myogenic potential in vitro (De Bari, C., F. Dell'Accio, P. Tylzanowski, and F.P. Luyten. 2001. Arthritis ...

Epitope mapping and specificity of the anti-alpha-synuclein monoclonal antibody Syn-1 in mouse brain and cultured cell lines.

Perrin, RJ; Payton, JE; Barnett, DH; Wraight, CL; Woods, WS; Ye, L; George, JM (2003-10-02)

While alpha- and beta-synuclein largely overlap in their expression in the vertebrate brain, only alpha-synuclein accumulates in the fibrillar aggregates typical of Parkinson's disease. It is thus critical to have immunological ...

Implications of the problem orientated medical record (POMR) for research using electronic GP databases: a comparison of the Doctors Independent Network Database (DIN) and the General Practice Research Database (GPRD).

Carey, IM; Cook, DG; De Wilde, S; Bremner, SA; Richards, N; Caine, S; Strachan, DP; Hilton, SR (2003-09-30)

BACKGROUND: The General Practice Research Database (GPRD) and Doctor's Independent Network Database (DIN), are large electronic primary care databases compiled in the UK during the 1990s. They provide a valuable resource ...

Quantitative analysis of human immunoregulatory cytokines by electrochemiluminescence method.

Sennikov, SV; Krysov, SV; Injelevskaya, TV; Silkov, AN; Grishina, LV; Kozlov, VA (2003-04-01)

Quantitative analysis of human immunoregulatory cytokines in physiological media and cell cultures plays an important role in fundamental and clinical research. Here we describe the quantification of interleukin (IL)-2, ...

Linkage analysis of cross-sectional and longitudinally derived phenotypic measures to identify loci influencing blood pressure.

Shephard, N; Falcaro, M; Zeggini, E; Chapman, P; Hinks, A; Barton, A; Worthington, J; Pickles, A; John, S (2003-12-31)

BACKGROUND: The design of appropriate strategies to analyze and interpret linkage results for complex human diseases constitutes a challenge. Parameters such as power, definition of phenotype, and replicability have to be ...

Community mental health care in Europe--an overview.

Priebe, S (2003)

Europe shares some historical roots of modern psychiatry. Even before the 19th century, there had been institutions for the mentally ill, such as the Bethlem in London which was founded more than 750 years ago, and organised ...